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Message: <blockquote data-quote="Oldvatr" data-source="post: 2460882" data-attributes="member: 196898">My research into c=peptide has unearthed the following study<a href="https://onlinelibrary.wiley.com/doi/10.1111/pedi.12609" target="_blank">https://onlinelibrary.wiley.com/doi/10.1111/pedi.12609</a>It may explain why TOFI are  more likely to be diagnosed T1D since low c-peptide tracks low BMI.This effect does extend into T2D land too<a href="https://pubmed.ncbi.nlm.nih.gov/15049937/" target="_blank">https://pubmed.ncbi.nlm.nih.gov/15049937/</a> Neither of these studies appears to quantify the effect.Studies of this nature seem to be primarily associated with T1D and hence are pediatric, so the China study above seems to be fairly unique in observing T2D adults.But it seems there may be an effect on c-peptide due to body weight that may extend to adults.  It may explain in part why the Newcastle Diet studies showed that insulin levels decreased during the trial.  It may be a confounder to that study.</blockquote>

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