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B12 And Metformin
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<blockquote data-quote="kitedoc" data-source="post: 1843578" data-attributes="member: 468714"><p>Could I try to untangle something here to make sure everyone is on the same page.? The following is taken from references and is not medical advice or opinion.</p><p>The cause of low B12 due to Metformin is unknown, according to diabetesselfmanagement.com.</p><p>In contrast pernicious anaemia (PA) is caused by antibodies attacking certain cells in the stomach which produce a substance called intrinsic factor. IF apparently is needed to enable B12 to be absorbed in the last part of the small intestine. (see webmd.com - What to know about Vitamin b12. and percious-anaemia.org )So B12 injections are the usual treatment. </p><p>But tests for PA are not 100% accurate. (pernicious-anaemia.org)</p><p>Webmed lists other causes of low B12 as infestation with fish tapeworm ( from eating raw fish) and malabsorption of B12 due to coeliac disease, Crohn's disease and bacterial infections and, as was mentioned in another quote, diets deplete in B12 such as a vegan diet (if not supplemented by addition of B12). There are some thyroid and lupus conditions also show up as possible causes.</p><p>Also to note is that usual serum B12 blood tests in pregnancy are not necessarily accurate. (active-B12.com)</p></blockquote><p></p>
[QUOTE="kitedoc, post: 1843578, member: 468714"] Could I try to untangle something here to make sure everyone is on the same page.? The following is taken from references and is not medical advice or opinion. The cause of low B12 due to Metformin is unknown, according to diabetesselfmanagement.com. In contrast pernicious anaemia (PA) is caused by antibodies attacking certain cells in the stomach which produce a substance called intrinsic factor. IF apparently is needed to enable B12 to be absorbed in the last part of the small intestine. (see webmd.com - What to know about Vitamin b12. and percious-anaemia.org )So B12 injections are the usual treatment. But tests for PA are not 100% accurate. (pernicious-anaemia.org) Webmed lists other causes of low B12 as infestation with fish tapeworm ( from eating raw fish) and malabsorption of B12 due to coeliac disease, Crohn's disease and bacterial infections and, as was mentioned in another quote, diets deplete in B12 such as a vegan diet (if not supplemented by addition of B12). There are some thyroid and lupus conditions also show up as possible causes. Also to note is that usual serum B12 blood tests in pregnancy are not necessarily accurate. (active-B12.com) [/QUOTE]
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