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B12 And Metformin
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<blockquote data-quote="kitedoc" data-source="post: 2066716" data-attributes="member: 468714"><p>Hi [USER=388174]@SimonCrox[/USER],</p><p>I found a study if 80 Dutch patient with newly diagnosed CD, compared to 24 healthy people, with incidence of B 12 deficiency reported in CD patients of 19% ( 67% with zinc deficiency)!. Apparently no correlation of extent of intestinal damage on biopsy with nutritional status. <a href="https://doi.org/10.3390/nu5103975" target="_blank">https://doi.org/10.3390/nu5103975</a></p><p>The guy with 5 loading doses, averages out at some 0.85 mcg B12 per day for the 16 years, but if the minimum daily B12 supplement was 1 mcg daily, maybe he was partly absobing B12?</p><p>Agree that i.m. sounds like the more reassuring route, even if more painful.</p><p>What is perhaps under recognised is undiagnosed B12 deficiency and CD in pregnancy, but with risk of derailing the thread I will leave things there. Best Wishes</p></blockquote><p></p>
[QUOTE="kitedoc, post: 2066716, member: 468714"] Hi [USER=388174]@SimonCrox[/USER], I found a study if 80 Dutch patient with newly diagnosed CD, compared to 24 healthy people, with incidence of B 12 deficiency reported in CD patients of 19% ( 67% with zinc deficiency)!. Apparently no correlation of extent of intestinal damage on biopsy with nutritional status. [URL]https://doi.org/10.3390/nu5103975[/URL] The guy with 5 loading doses, averages out at some 0.85 mcg B12 per day for the 16 years, but if the minimum daily B12 supplement was 1 mcg daily, maybe he was partly absobing B12? Agree that i.m. sounds like the more reassuring route, even if more painful. What is perhaps under recognised is undiagnosed B12 deficiency and CD in pregnancy, but with risk of derailing the thread I will leave things there. Best Wishes [/QUOTE]
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