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Message: <blockquote data-quote="DiabeticBloke1" data-source="post: 2565419" data-attributes="member: 564428">Hello.  This is an interesting thread because I (and probably many others like me) had never considered B12 as a factor.  I have been on Metformin since early 2011 (and diaformin for a few years prior to that).  I was then switched to Jardiamet (empagliflozin & metformin) in 2016 and then back to just metformin in early 2022 - due to some Australian government ruling not permitting us to combine empagliflozin and Ozempic (semaglutide).  In a blood test a couple of years ago, my B12 levels were extremely low.  I had to have a few B12 injections.  After the first course, my nurse (at my GP practice) suggested that instead of the needle I should have the B12 spray (under the tongue, once a week), which is less painful and a lot easier.  Obviously you'll need your own GP's advice, but this fairly cheap, OTC medicine (BioCeuticals B12 spray) is working for me.  My B12 levels are back to "normal" and I include the B12 test in my quarterly blood tests, just to be sure.  Cheers, DB1.</blockquote>

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