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Type 1 Diabetes
Bleeding after injecting insulin
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<blockquote data-quote="SimonCrox" data-source="post: 1590633" data-attributes="member: 388174"><p>I think it is to do with the slow release mechanism of lantus.</p><p>Most insulins are same acidity/alkalinity (pH) as humans ( about 7.4); Lantus is made to be insoluble at human pH and needs to be slightly acidic to dissolve. So the lantus injection is a slightly acidic solution to keep it soluble, and then in human tissue it is neutralised to human pH at which the Lantus is insoluble; it then slowly dissolves, hence its slow action. In the past, some of the Zinc insulins eg Humulin Z used to sting a bit cos of the large amount of zinc, they said, but I am not sure about this. Other insulins are human pH and this might be why they are less likely to sting</p><p>Best wishes</p></blockquote><p></p>
[QUOTE="SimonCrox, post: 1590633, member: 388174"] I think it is to do with the slow release mechanism of lantus. Most insulins are same acidity/alkalinity (pH) as humans ( about 7.4); Lantus is made to be insoluble at human pH and needs to be slightly acidic to dissolve. So the lantus injection is a slightly acidic solution to keep it soluble, and then in human tissue it is neutralised to human pH at which the Lantus is insoluble; it then slowly dissolves, hence its slow action. In the past, some of the Zinc insulins eg Humulin Z used to sting a bit cos of the large amount of zinc, they said, but I am not sure about this. Other insulins are human pH and this might be why they are less likely to sting Best wishes [/QUOTE]
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