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<blockquote data-quote="Oldvatr" data-source="post: 1606552" data-attributes="member: 196898"><p>There is a clue in the blog that tells us why. The blog tests used venous blood samples for both the lab check and the meters. Thus there is not a like for like comparison, Finger prick testers measure interstitial fluid, not blood, so have different calibration, and this used to be called Whole Blood Calibration, The lab meter is calibrated for what is called plasma calibration, which used to be significantly different. Modern home meters and their chemistry still measure whole blood, but are mathematically adjusted so that they mimic Plasma Lab meters, but the methods used are not exact due to the difference in what the different fluids contain. For a start, home bgl meters are more affected by Haematocrit value, as well as some other chemicals such as sugar alcohols eg malitol, which the Lab meters are not.</p><p></p><p>Because of copyright constraints each manufactuter will use different chemistries and sensors to measure the glucose, and this too can skew their results. According to ISO, modern home meters must meet certain accuracy standards, but they only need to do this once under ideal lab conditions. They are not verified on production to meet these standards either on a batch basis, or a per meter basis, or against other meters. So once their box has passed the test, they are free to sell us whatever they like, so long as it appears to do the job no one outside will know if they are in spec or way out for a given reading.</p></blockquote><p></p>
[QUOTE="Oldvatr, post: 1606552, member: 196898"] There is a clue in the blog that tells us why. The blog tests used venous blood samples for both the lab check and the meters. Thus there is not a like for like comparison, Finger prick testers measure interstitial fluid, not blood, so have different calibration, and this used to be called Whole Blood Calibration, The lab meter is calibrated for what is called plasma calibration, which used to be significantly different. Modern home meters and their chemistry still measure whole blood, but are mathematically adjusted so that they mimic Plasma Lab meters, but the methods used are not exact due to the difference in what the different fluids contain. For a start, home bgl meters are more affected by Haematocrit value, as well as some other chemicals such as sugar alcohols eg malitol, which the Lab meters are not. Because of copyright constraints each manufactuter will use different chemistries and sensors to measure the glucose, and this too can skew their results. According to ISO, modern home meters must meet certain accuracy standards, but they only need to do this once under ideal lab conditions. They are not verified on production to meet these standards either on a batch basis, or a per meter basis, or against other meters. So once their box has passed the test, they are free to sell us whatever they like, so long as it appears to do the job no one outside will know if they are in spec or way out for a given reading. [/QUOTE]
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