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Message: <blockquote data-quote="thhpe" data-source="post: 2540095" data-attributes="member: 490579">AloeSvea states:I get c-peptide tests done from time to time, and always fasting, along with other blood lipid and HBA1c tests. Not a problem.Perhaps I should elaborate more : C-peptide is part of the proinsulin molecule, the C shape peptide that is being cleave off to produce the insulin molecule.  So for every insulin molecule produced a C-peptide molecule is also produced. If a person blood glucose level is low e.g. 4.4mmol/l, he/she would not be producing any insulin and C-peptide as doing so will get that person into hypo.  That is the reason to diagnose whether any person is still producing insulin, the C-peptide test is only meaningful when the blood glucose shall be around 7mmol/l or higher.  As that person if still able to produce insulin will reflect that capability in the C-peptide test.Of course to do a C-peptide test on fasting is not a problem to the testing lab.  The question is, is it meaningful without knowing whether any insulin is produced hence a meaningful measurement of C-peptide.  In my case it is a waste of money doing on fasting at < 5mmol/l blood glucose.</blockquote>

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