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Type 2 Diabetes
Can hba1c be too low?
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<blockquote data-quote="pavlosn" data-source="post: 706670" data-attributes="member: 22572"><p>I understand that generally A1c is considered the more reliable test than home testing.</p><p></p><p>But as you have shown in the graphs and links you have provided the relationship between A1c and average glucose levels, although well established is one that can only allow you to estimate your average glucose within a certain range for a specific confidence level.</p><p></p><p>The main disadvantage of home glucose tests, even setting aside the +/-15% monitor accuracy limitations, are that they are snapshots in time, only giving you a measure of your level at certain specific points in time. Of course with frequent testing you probably end up with several hundreds of these snapshots over time, giving you a better overall picture; but still not a complete picture.</p><p></p><p>As you also state in an earlier post hba1c and average glucose levels although related are not the same thing. Hba1c is an indicator of increased risk independently to its relationship to average glucose levels. There are May well be other factors affecting hba1c beyond glucose levels.</p><p></p><p>For one two factors that may affect it or even invalidate it is if there is unusual characteristics in ones hemoglobin or if the lifespan of ones blood cells. </p><p></p><p>Perhaps using your hba1c count as a means of comparing with earlier counts you may have may be more meaningful than comparing against absolute references but the latter seems to be what the medical profession is doing with diabetes being diagnosed for instance beyond a set predefined hba1c score.</p></blockquote><p></p>
[QUOTE="pavlosn, post: 706670, member: 22572"] I understand that generally A1c is considered the more reliable test than home testing. But as you have shown in the graphs and links you have provided the relationship between A1c and average glucose levels, although well established is one that can only allow you to estimate your average glucose within a certain range for a specific confidence level. The main disadvantage of home glucose tests, even setting aside the +/-15% monitor accuracy limitations, are that they are snapshots in time, only giving you a measure of your level at certain specific points in time. Of course with frequent testing you probably end up with several hundreds of these snapshots over time, giving you a better overall picture; but still not a complete picture. As you also state in an earlier post hba1c and average glucose levels although related are not the same thing. Hba1c is an indicator of increased risk independently to its relationship to average glucose levels. There are May well be other factors affecting hba1c beyond glucose levels. For one two factors that may affect it or even invalidate it is if there is unusual characteristics in ones hemoglobin or if the lifespan of ones blood cells. Perhaps using your hba1c count as a means of comparing with earlier counts you may have may be more meaningful than comparing against absolute references but the latter seems to be what the medical profession is doing with diabetes being diagnosed for instance beyond a set predefined hba1c score. [/QUOTE]
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