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Can hba1c be too low?
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<blockquote data-quote="pmtbrew" data-source="post: 793857" data-attributes="member: 162438"><p>I've read this thread with great interest, since being diagnosed in August with a A1C of 112mmol/mol (~12%), I managed to get it down to 46mmol/mol in December and now its down to 37mmol/mol (the fact that I restrict carb intake and exercise for around 10hrs a week does not enter into the equations)</p><p></p><p>Quick bit about me, I'm 38 and have a BMI of 23 so I don't fall into the 'normal' range for diabetics (the first question I ask when I see someone new is how many patients they have seen like me). </p><p></p><p>The nurse has advised me to remove gliclazide (40mg/day), which I've tried but the A1C jumps up to 50mmol/mol by the third day (with an average of 2hr cardio exercise) so I have went back on the gliclazide very quickly and its taken almost 2 weeks for the levels to return back to normal (I use a Freestyle Libre so have enough data to see short term changes in blood sugars).</p><p></p><p>Having looked into the NICE guidance and the primary literature (some of them), the recommended levels for a diabetic (48mmol/mol or 5.5%) has a risk of developing complications greater than 1 (more likely) so I do not understand why the levels are not lower (I would say 37mmol/mol should be the target as the risk approaches close to 1).</p><p></p><p>One point that has not been made yet is the age of the diabetic, I have another 50 years (hopefully) to deal with my diabetes, so any increase risk would affect me more than a diabetic in their 60's. </p><p></p><p>I'm going to try to see if I can argue the case because of my age, I need to be allowed to have a tighter control of my blood sugars in order to prevent any complications later in life, I have my appointment on the 19th March so will come back with the outcome.</p></blockquote><p></p>
[QUOTE="pmtbrew, post: 793857, member: 162438"] I've read this thread with great interest, since being diagnosed in August with a A1C of 112mmol/mol (~12%), I managed to get it down to 46mmol/mol in December and now its down to 37mmol/mol (the fact that I restrict carb intake and exercise for around 10hrs a week does not enter into the equations) Quick bit about me, I'm 38 and have a BMI of 23 so I don't fall into the 'normal' range for diabetics (the first question I ask when I see someone new is how many patients they have seen like me). The nurse has advised me to remove gliclazide[I] [/I](40mg/day), which I've tried but the A1C jumps up to 50mmol/mol by the third day (with an average of 2hr cardio exercise) so I have went back on the gliclazide very quickly and its taken almost 2 weeks for the levels to return back to normal (I use a Freestyle Libre so have enough data to see short term changes in blood sugars). Having looked into the NICE guidance and the primary literature (some of them), the recommended levels for a diabetic (48mmol/mol or 5.5%) has a risk of developing complications greater than 1 (more likely) so I do not understand why the levels are not lower (I would say 37mmol/mol should be the target as the risk approaches close to 1). One point that has not been made yet is the age of the diabetic, I have another 50 years (hopefully) to deal with my diabetes, so any increase risk would affect me more than a diabetic in their 60's. I'm going to try to see if I can argue the case because of my age, I need to be allowed to have a tighter control of my blood sugars in order to prevent any complications later in life, I have my appointment on the 19th March so will come back with the outcome. [/QUOTE]
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