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<blockquote data-quote="In Response" data-source="post: 2428443" data-attributes="member: 527103"><p>If you are treating your diabetes with metformin, grapefruit is not a good idea.</p><p></p><p>“Some of the chemicals found in grapefruit can bind to and inactivate an enzyme in your body that’s found in your intestines and liver. This enzyme helps break down the medication you take.</p><p></p><p>Normally when you take a drug orally, it’s broken down slightly by enzymes before it reaches your bloodstream. This means that you receive a little less of the drug in your bloodstream than the amount you initially consumed.</p><p></p><p>But when the enzyme is inhibited — as it is when it interacts with the chemicals in grapefruit — there’s a dramatically larger amount of the drug that makes its way into your bloodstream. This leads to a higher risk of overdose.”</p><p></p><p>This has nothing to do with the carbs in grapefruit and is not the same for oranges.</p></blockquote><p></p>
[QUOTE="In Response, post: 2428443, member: 527103"] If you are treating your diabetes with metformin, grapefruit is not a good idea. “Some of the chemicals found in grapefruit can bind to and inactivate an enzyme in your body that’s found in your intestines and liver. This enzyme helps break down the medication you take. Normally when you take a drug orally, it’s broken down slightly by enzymes before it reaches your bloodstream. This means that you receive a little less of the drug in your bloodstream than the amount you initially consumed. But when the enzyme is inhibited — as it is when it interacts with the chemicals in grapefruit — there’s a dramatically larger amount of the drug that makes its way into your bloodstream. This leads to a higher risk of overdose.” This has nothing to do with the carbs in grapefruit and is not the same for oranges. [/QUOTE]
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