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Type 1 Diabetes
Confused by a Tresiba "Side Effects"
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<blockquote data-quote="pinewood" data-source="post: 2358883" data-attributes="member: 147474"><p>So according to multiple sources, one possible side effect of Tresiba is "upper respiratory tract infections". Even NovoNordisk themselves cite this as a possible side effect (see <a href="https://www.tresiba.com/content/dam/diabetes-patient/tresiba/aboutdiabetes/disease-state/Peds_Get_to_know_Tresiba.pdf" target="_blank">here</a>). Apparently a worrying 11.9% of adults using Tresiba have this "adverse reaction" and an even more concerning 23.9% get nasopharyngitis.</p><p></p><p>This has really confused me. I thought the only way to catch an "upper resprtatory tract infection" (or a cold) is from bacteria or a virus. Should they actually have said "<u><em><strong>increased susceptibil</strong></em><strong><em>ity to</em></strong></u> upper respiratory tract infections and colds"?</p><p></p><p>In any case, this is really concerning me. Do Lantus and other long acting insulins have these same issues? What is the mechanism that causes this; does Tresiba somehow reduce the effectiveness our immune system? I'm super concerned this could also translate into higher chance of catching COVID-19.</p><p></p><p>Seems crazy to me that a medicine can even be approved with such shockingly high figures? One in 4 people get nasopharyngitis from Tresiba? How is that even possible? Or is it just that it could have been a coincidence but they can't prove it either way so still have to list it as 23.9%?</p><p></p><p>I've been using Tresiba for a few years now and only recently saw this; I recently had a bad upper respiratory tract infection despite my partner and I not having not left the house for the preceding 2 weeks, so that's why this took my interest as now I'm wondering if Tresiba could have been responsible?</p></blockquote><p></p>
[QUOTE="pinewood, post: 2358883, member: 147474"] So according to multiple sources, one possible side effect of Tresiba is "upper respiratory tract infections". Even NovoNordisk themselves cite this as a possible side effect (see [URL='https://www.tresiba.com/content/dam/diabetes-patient/tresiba/aboutdiabetes/disease-state/Peds_Get_to_know_Tresiba.pdf']here[/URL]). Apparently a worrying 11.9% of adults using Tresiba have this "adverse reaction" and an even more concerning 23.9% get nasopharyngitis. This has really confused me. I thought the only way to catch an "upper resprtatory tract infection" (or a cold) is from bacteria or a virus. Should they actually have said "[U][I][B]increased susceptibil[/B][/I][B][I]ity to[/I][/B][/U] upper respiratory tract infections and colds"? In any case, this is really concerning me. Do Lantus and other long acting insulins have these same issues? What is the mechanism that causes this; does Tresiba somehow reduce the effectiveness our immune system? I'm super concerned this could also translate into higher chance of catching COVID-19. Seems crazy to me that a medicine can even be approved with such shockingly high figures? One in 4 people get nasopharyngitis from Tresiba? How is that even possible? Or is it just that it could have been a coincidence but they can't prove it either way so still have to list it as 23.9%? I've been using Tresiba for a few years now and only recently saw this; I recently had a bad upper respiratory tract infection despite my partner and I not having not left the house for the preceding 2 weeks, so that's why this took my interest as now I'm wondering if Tresiba could have been responsible? [/QUOTE]
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