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Message: <blockquote data-quote="Chris24Main" data-source="post: 2740057" data-attributes="member: 585131">As it happens, I was doing a really deep dive into Metformin at the weekend, trying to get a grip on how it actually works...Almost none of what I learned is going to help anyone, but at the higher level, I totally agree with everything already said.It does have a really interesting history, being a naturally occurring plant, and thus herbal medicine, used since the middle ages.[edit - realise that this could be mis-interpreted - I only mean that nobody, for example, really cares how metformin interacts with complex 1 in the electron chain transport  - it's just too low level - and often the final answer is still "we just don't know all the ways that metformin actually works]</blockquote>

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