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<blockquote data-quote="JohnEGreen" data-source="post: 2236283" data-attributes="member: 223921"><p>Remdesivir a drug used successively against MERS and SARS also seems to be effective with Covid 19</p><p></p><p></p><p>"What our study showed was that remdesivir essentially mimics one of the natural building blocks for RNA synthesis necessary for genome replication of the virus. Enzymes within the virus are synthesizing the viral RNA genome with these building blocks, but they mix up the bits they need with the drug. Once the drug is incorporated into the growing RNA chain, the virus can no longer replicate,"explained Götte.</p><p>He said the next step is to wait for results from ongoing clinical trials with remdesivir, which are expected by the end of April. Even then, that won't be the end of the story, he cautioned.</p><p>"It's likely we'll need more than one drug to properly fight emerging diseases like COVID-19, as we have with HIV and hepatitis C virus infections," Götte said.</p><p>"Ideally, we will have a couple of drugs because certain strains could be resistant to certain treatments."</p><p></p><p><a href="https://www.sciencedaily.com/releases/2020/02/200227122123.htm" target="_blank">https://www.sciencedaily.com/releases/2020/02/200227122123.htm</a></p></blockquote><p></p>
[QUOTE="JohnEGreen, post: 2236283, member: 223921"] Remdesivir a drug used successively against MERS and SARS also seems to be effective with Covid 19 "What our study showed was that remdesivir essentially mimics one of the natural building blocks for RNA synthesis necessary for genome replication of the virus. Enzymes within the virus are synthesizing the viral RNA genome with these building blocks, but they mix up the bits they need with the drug. Once the drug is incorporated into the growing RNA chain, the virus can no longer replicate,"explained Götte. He said the next step is to wait for results from ongoing clinical trials with remdesivir, which are expected by the end of April. Even then, that won't be the end of the story, he cautioned. "It's likely we'll need more than one drug to properly fight emerging diseases like COVID-19, as we have with HIV and hepatitis C virus infections," Götte said. "Ideally, we will have a couple of drugs because certain strains could be resistant to certain treatments." [URL]https://www.sciencedaily.com/releases/2020/02/200227122123.htm[/URL] [/QUOTE]
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