Nometype1andproud
Well-Known Member
- Messages
- 93
- Type of diabetes
- Type 1
Hello folks I've been prescribed this to try and counteract insulin resistance and crazy weight gain. I cannot tolerate metformin and hba1c shot up from 65 to 77 and 2 stone weight gain in last year.
Any success stories?
I'm a type 2, on Dapagliflozin, @TypeZero is right, drink, drink and drink some more, at 1st you'll never be away from the loo, but your body does get used to being more hydrated, 6 years & not one dose of thrush (you watch me get one now), it can also cause (rare in t2) DKA with no symptoms especially if you follow a low carb way of eating
I take 1 10mg tablet once a day (first thing for me, but I don't think it matters when you take it) When I was just on that and metformin I was losing, but they've put me back on the gliclazide too, which prods your pancreas to make more insulin, that kind of counteracts it (but I've not put any back on which is a bonus, the 1st time they had me on the glic I gained almost 2 stone in a month without changing any of my eating habits), it is a bit of an appetite suppressant too, but I can eat when I'm not hungry!Did you lose any weight since you’re technically urinating the sugar out?
Also do you take it before every meal or like once a day
If you have double diabetes i.e. both insulin resistant AND needing to inject insulin then I'd have thought some of the dietary advice offered to the classic insulin resistant type 2s would be appropriate i.e. to reduce carbs (and bolus obviously). Did your team mention this as an option?
This drug works by getting you to pee out some of your glucose (developed from observing how untreated type 1s excrete glucose!) but if you imagine how high your glucose goes when you do not inject insulin and even when not eating I think the doctors are expecting too much from this drug and as has been pointed out it comes with side effects.
If you can turn off the glucose tap by eating a little less bread, pasta, rice and avoiding sugar that might be a lot more effective than just the drug by itself. Sorry that I don't have any type 1 experience with this class of drug other than a type 2 friend who took it and managed to shed a little weight but not much.
I never used anything apart from insulin but have been doing tonnes of research.
Dapagliflozin may cause urinary tract infections because the glucose concentrations of your urine increases so watch out for that.
the point is surely that if you reduce your carb intake you reduce the sugar levels in your blood and may not need additional meds to deal with those levels? You can adjust your insulin to compensate for lower carb levels. That is what one of my T1 friends does.I'm on an insulin pump, I carb count 24/7 due to being on the pump so am well aware of my carb sensitivity. I was merely after other peoples experience of this particular medication due to my current position. Thank you for your reply though
Also on a pump and carb count (but lazily) to avoid weight gain and creeping up of insulin needs. I hate carb counting so my lazy approach is to avoid them as much as possible! Just something you may want to consider and if you do take the sglt2 inhibitor type drug I'd be interested to know how you get on!I'm on an insulin pump, I carb count 24/7 due to being on the pump so am well aware of my carb sensitivity. I was merely after other peoples experience of this particular medication due to my current position. Thank you for your reply though
the point is surely that if you reduce your carb intake you reduce the sugar levels in your blood and may not need additional meds to deal with those levels? You can adjust your insulin to compensate for lower carb levels. That is what one of my T1 friends does.
Also on a pump and carb count (but lazily) to avoid weight gain and creeping up of insulin needs. I hate carb counting so my lazy approach is to avoid them as much as possible! Just something you may want to consider and if you do take the sglt2 inhibitor type drug I'd be interested to know how you get on!
So the average diet has about 240g a day so you're right to say your diet isn't carb heavy but is higher than what I'd eat as a low carber (about 90g a day max.) and yet you're needing more insulin to cover it which then needs you needing more and more. A good analogy is the clothes are the carbs your insulin/you is trying to stuff into an overfilled suitcase (your cells). Some people have less room in their cells than others and others can use huge amounts of insulin but simply get fatter without being insulin resistant. As a type 1 you are obviously very aware of what you eat plus the amounts of insulin you're injecting.I don't have a particularly carb heavy diet to begin with and since improving my hba1c I am healthier on paper but a **** sight bigger and now the resistance I have a max 200g carb a day at my most
So the average diet has about 240g a day so you're right to say your diet isn't carb heavy but is higher than what I'd eat as a low carber (about 90g a day max.) and yet you're needing more insulin to cover it which then needs you needing more and more. A good analogy is the clothes are the carbs your insulin/you is trying to stuff into an overfilled suitcase (your cells). Some people have less room in their cells than others and others can use huge amounts of insulin but simply get fatter without being insulin resistant. As a type 1 you are obviously very aware of what you eat plus the amounts of insulin you're injecting.
I am not trying to get you to eat a lower carb diet or criticise what you are doing but just trying to open your mind to the idea that eating more protein and fat but less carbs may help you reduce your insulin resistance better than drugs alone. The hba1c is only 1 part of your results because if you're insulin resistant and having to take more insulin then this is linked to cardiovascular risk and not just from the weight gain.
Thanks for replying! I will only be on a small dose due to being type 1 but do have a lot of weight to shift so am willing to give it a go.
Sorry to hear you have been so poorly wishing you a speedy recovery.
Will do!Do let us know if your basal decreases and by how much
Thanks
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