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Diabetes drugs, steroids and unknown problem
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<blockquote data-quote="Blackwater5" data-source="post: 2509806" data-attributes="member: 552414"><p>Apologies bin advance for a long post and if admins want to move to more appropriate categories they're welcome to do so.</p><p>First, I lost a lot of weight within a year, up to 20 kg, taking me from slightly ovrerweight to close to underweight. During early investigations I nwas tested for hbA1c, started at 43, then 48 within 2 months, then 57 4 months later. I was given linagliptin as a first drug *told I couldn't take metformin) and within 2 to 3 weeks I had hives then huge blisters. This was diagnosed as bullous pemphigoid (autoimmune skin disease) and I was given oral and topical steroids for 2 weeks after biopsy. The lipigliptin plus balanced diet (was given no more info)meant my hbA1c only went up to 57 in 4 months. The steroids made me feel ill, made my diabetes uncontrollable and increased blood pressure. My GP and myself only received the dermatology letter 6 weeks after I'd stopped the 30 mg prednisolone suddenly and said that I had to reduce by 5 mg a week, that it had started to resolve. But I'd stopped steroids and my diabetes was controlled although my blood pressure was swinging from high to low and I still felt ill. I avoided returning for the blisters for a couple of months because the effects of steroids was so bad, but eventually had to as I was almost covered with scabs and blisters.</p><p>In the meantime I was given empaglifloxin (Jardiance) 10 mg a day, plus an ACE inhibitor which I stopped after 4 days due to permanent terrible headaches and pink spots on my legs. Since3 then my bg has been controlled until the steroids again. Now my fasting level is 4 to 6 mmol/L in the morning before taking steroids, then shoots up to an average between 9 and 13 and my BP has increased, plus swollen feet and ankles.</p><p>I'm still losing weight and although I try to keep my carbs lowish I find that I have to have carbs as I can't lose more weight and eggs in particular increase my bg.</p><p>Does anyone have ideas on how to control bg while on steroids without a lot of exercise (too painful and drops weight), a diet that is not low carb (although I try to keep carbs lowish) and gain weight?</p><p></p><p>Also it has now been proved that one side-effect of gliptins can be pemphigoid which is incurable and can be fatal either from sepsis or steroid effects?</p><p></p><p>I've not posted here for some time. since I was panicking and in urgent need of information after first diagnosis early this year..</p></blockquote><p></p>
[QUOTE="Blackwater5, post: 2509806, member: 552414"] Apologies bin advance for a long post and if admins want to move to more appropriate categories they're welcome to do so. First, I lost a lot of weight within a year, up to 20 kg, taking me from slightly ovrerweight to close to underweight. During early investigations I nwas tested for hbA1c, started at 43, then 48 within 2 months, then 57 4 months later. I was given linagliptin as a first drug *told I couldn't take metformin) and within 2 to 3 weeks I had hives then huge blisters. This was diagnosed as bullous pemphigoid (autoimmune skin disease) and I was given oral and topical steroids for 2 weeks after biopsy. The lipigliptin plus balanced diet (was given no more info)meant my hbA1c only went up to 57 in 4 months. The steroids made me feel ill, made my diabetes uncontrollable and increased blood pressure. My GP and myself only received the dermatology letter 6 weeks after I'd stopped the 30 mg prednisolone suddenly and said that I had to reduce by 5 mg a week, that it had started to resolve. But I'd stopped steroids and my diabetes was controlled although my blood pressure was swinging from high to low and I still felt ill. I avoided returning for the blisters for a couple of months because the effects of steroids was so bad, but eventually had to as I was almost covered with scabs and blisters. In the meantime I was given empaglifloxin (Jardiance) 10 mg a day, plus an ACE inhibitor which I stopped after 4 days due to permanent terrible headaches and pink spots on my legs. Since3 then my bg has been controlled until the steroids again. Now my fasting level is 4 to 6 mmol/L in the morning before taking steroids, then shoots up to an average between 9 and 13 and my BP has increased, plus swollen feet and ankles. I'm still losing weight and although I try to keep my carbs lowish I find that I have to have carbs as I can't lose more weight and eggs in particular increase my bg. Does anyone have ideas on how to control bg while on steroids without a lot of exercise (too painful and drops weight), a diet that is not low carb (although I try to keep carbs lowish) and gain weight? Also it has now been proved that one side-effect of gliptins can be pemphigoid which is incurable and can be fatal either from sepsis or steroid effects? I've not posted here for some time. since I was panicking and in urgent need of information after first diagnosis early this year.. [/QUOTE]
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