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Diabetes: Have We Got It All Wrong? (T2D)
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<blockquote data-quote="AloeSvea" data-source="post: 2147789" data-attributes="member: 150927"><p><span style="font-family: 'Arial'">Another way of looking at insulin resistance is that as it is a default action - ie that when we are imbibing food and drink, toxins etc, that causes a too high insulin production, over time, <em>IR is actually our body's first line of defence</em>. (Along with storing excess energy in body fat in the belly first then all over.)</span></p><p><span style="font-family: 'Arial'"></span></p><p><span style="font-family: 'Arial'">If only lowered insulin production was the worst medium or long term consequence of IR! In fact, kidney breakdown seems to be the bigger problem. You can see this disease progression very well in the doco series from Aotearoa/NZ 'The disease that is killing my family' (available on youtube/online). (I know - horrible title, but, a son of a man who dies in the course of the doco from diabetic kidney failure is the doco-maker, so....) </span></p><p><span style="font-family: 'Arial'"></span></p><p><span style="font-family: 'Arial'">Kidney breakdown (where dialysis is called for) is big-time in Polynesia generally, which is shown in one of the docos in particular in the series. (And the limbs rotting 'thing', with amputations.)</span></p><p><span style="font-family: 'Arial'"></span></p><p><span style="font-family: 'Arial'">Severe insulin resistance diabetes has a different disease make-up and progression - ie the kidney breakdown (according to the Swedish endos/researchers at Lund Uni where I get this info from) to what the same Swedes call mild obesity and mild age related diabetes (the latter two accounts for 66% of all diabetes including auto-immune diabetes). They make the very reasonable point that these different kinds of diabetes need different treatments.</span></p><p><span style="font-family: 'Arial'"></span></p><p><span style="font-family: 'Arial'">Severe insulin resistance diabetes affects about 15% of all diabetes sufferers (at least in Sweden, numbers as above care of Lund Uni researchers). Those prone to this type of diabetes have a different gene/hormone profile to the rest - my own understanding is that it affects those with a lean and muscular body type (under 'normal' conditions), hence its devastating effects in Polynesian countries, Aotearoa included. </span></p></blockquote><p></p>
[QUOTE="AloeSvea, post: 2147789, member: 150927"] [FONT=Arial]Another way of looking at insulin resistance is that as it is a default action - ie that when we are imbibing food and drink, toxins etc, that causes a too high insulin production, over time, [I]IR is actually our body's first line of defence[/I]. (Along with storing excess energy in body fat in the belly first then all over.) If only lowered insulin production was the worst medium or long term consequence of IR! In fact, kidney breakdown seems to be the bigger problem. You can see this disease progression very well in the doco series from Aotearoa/NZ 'The disease that is killing my family' (available on youtube/online). (I know - horrible title, but, a son of a man who dies in the course of the doco from diabetic kidney failure is the doco-maker, so....) Kidney breakdown (where dialysis is called for) is big-time in Polynesia generally, which is shown in one of the docos in particular in the series. (And the limbs rotting 'thing', with amputations.) Severe insulin resistance diabetes has a different disease make-up and progression - ie the kidney breakdown (according to the Swedish endos/researchers at Lund Uni where I get this info from) to what the same Swedes call mild obesity and mild age related diabetes (the latter two accounts for 66% of all diabetes including auto-immune diabetes). They make the very reasonable point that these different kinds of diabetes need different treatments. Severe insulin resistance diabetes affects about 15% of all diabetes sufferers (at least in Sweden, numbers as above care of Lund Uni researchers). Those prone to this type of diabetes have a different gene/hormone profile to the rest - my own understanding is that it affects those with a lean and muscular body type (under 'normal' conditions), hence its devastating effects in Polynesian countries, Aotearoa included. [/FONT] [/QUOTE]
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