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Diabetes: Have We Got It All Wrong? (T2D)
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<blockquote data-quote="alienskin" data-source="post: 2149825" data-attributes="member: 508073"><p>I've listened quickly again, and I can't find the exact quote so apologies there, but it doesn't change much. This is what he said word for word:</p><p></p><p>"You have both resistance and supersensitivity. <em>That's not really possible</em>. And that's the central paradox if IR, and it doesn't really make any sense...it's like making a brick wall with no bricks. <em>It's just impossible.</em>"</p><p></p><p>This is simply nonsense. The above paper shows exactly the split-pathway mechanism which makes it possible, and this has been around for years. He puts great store in the present model not being possible, but in fact it is very possible.</p></blockquote><p></p>
[QUOTE="alienskin, post: 2149825, member: 508073"] I've listened quickly again, and I can't find the exact quote so apologies there, but it doesn't change much. This is what he said word for word: "You have both resistance and supersensitivity. [I]That's not really possible[/I]. And that's the central paradox if IR, and it doesn't really make any sense...it's like making a brick wall with no bricks. [I]It's just impossible.[/I]" This is simply nonsense. The above paper shows exactly the split-pathway mechanism which makes it possible, and this has been around for years. He puts great store in the present model not being possible, but in fact it is very possible. [/QUOTE]
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