being a LCHF'er, I hoping so, I hope I have enough beta cells left, to last till something major goes, like a heart failure or something when I'm a 100"50% of Type 2 diabetics will be on insulin within 6 to 10 years of diagnosis", therefore, quite clearly, 50% WILL NOT be on insulin and I bet that the low-carbers will be in the "Nots".
Sally
RESEARCH DESIGN AND METHODS — A total of 110 patients with type 2 diabetes (55 with no retinopathy [the primary prevention cohort] and 55 with simple retinopathy [the secondary intervention cohort]) were randomly assigned to multiple insulin injection therapy (MIT) groups and administered three or more daily insulin injections or assigned to conventional insulin injection therapy (CIT) groups and administered one or two daily intermediate-acting insulin injections. Worsening of microvascular complications was regularly assessed during 8 years. Two or more steps up in the 19 stages of the modified Early Treatment of Diabetic Retinopathy Study classification in retinopathy and one or more stages up among three stages in nephropathy (normoalbuminuria, microalbuminuria, and albuminuria) were defined as worsening of complications.
RESULTS — In both primary prevention and secondary intervention cohorts, the cumulative percentages of worsening in retinopathy and nephropathy were significantly lower (P < 0.05) in the MIT group than in the CIT group. In neurological tests after 8 years, the MIT group showed significant improvement (P < 0.05) in the median nerve conduction velocities (motor and sensory nerves), whereas the CIT group showed significant deterioration (P < 0.05) in the nerve conduction velocities and vibration threshold. From this study, the glycemic threshold to prevent the onset and progression of diabetic microvascular complications was as follows: HbA1c <6.5%, fasting blood glucose concentration <110 mg/dl, and 2-h postprandial blood glucose concentration <180 mg/dl.
CONCLUSIONS — Intensive glycemic control can delay the onset and progression of the early stages of diabetic microvascular complications in Japanese patients with type 2 diabetes.
@Ruth B and @nooboots I guess after we lose weight and get our insulin resistance down through diet and exercise, whether/when we move onto insulin will depend on, how many and how good are our beta cells.
they say at T2 diagnosis about half of our beta cells are wacked
http://care.diabetesjournals.org/content/34/Supplement_2/S258.full
There is a progressive deterioration in β-cell function in patients with type 2 diabetes. At diagnosis, islet function may be reduced by up to 50% compared with healthy control subjects, and there is also likely to be a reduction in β-cell mass of up to 60%. The reduction in β-cell mass is due to accelerated apoptosis. Currently, few pharmacological therapies address this reduction in β-cell mass and function. This means that patients are generally subjected to an increasing polypharmacy to control their diabetes, with most eventually being treated by insulin
We use cookies and similar technologies for the following purposes:
Do you accept cookies and these technologies?
We use cookies and similar technologies for the following purposes:
Do you accept cookies and these technologies?