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Does badly managed diabetes affect memory?
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<blockquote data-quote="jjraak" data-source="post: 2107317" data-attributes="member: 493719"><p>Hi [USER=492004]@IronLioness[/USER]</p><p>sorry hear dad is causing you worries.</p><p></p><p>may well be just getting older...hope it is.</p><p></p><p>watched my mum slowly slip into alzheimer's/senile dementia..awful</p><p></p><p>so good your keeping an eye on him.</p><p></p><p>My OH her father is similar, we can't tell him, he thinks it's a game.</p><p>But he eats very sparingly, so the impact may be less then expected.</p><p></p><p>Have looked before when this has come up, and i suppose it does make sense.</p><p>if diabetes can cause neuropathy due to damage to nerve endings, how do we think the brain works..?</p><p></p><p>But does it mean its a definite..no.</p><p></p><p>i did a quick Dr google and found a US site, that suggests as do many others i'd wager that XYZ is the case.</p><p>So let me just quote the part is read and leave the link to source.</p><p></p><p><a href="https://www.goodrx.com/blog/ten-myths-about-metformin/" target="_blank">https://www.goodrx.com/blog/ten-myths-about-metformin/</a></p><p></p><p>"...</p><p><span style="font-size: 18px"><strong>4) Metformin causes dementia.</strong></span></p><p><em><strong>No. In fact, a recent <a href="http://www.neurologyadvisor.com/neurodegenerative-diseases/dementia-risk-reduced-metformin-type-2-diabetes/article/703995/" target="_blank">study</a> of 17,000 veterans with diabetes found that taking metformin was associated with a lower risk of dementia than other diabetes drugs known as sulfonylureas (like <a href="https://www.goodrx.com/glyburide" target="_blank">glyburide</a> and <a href="https://www.goodrx.com/glipizide" target="_blank">glipizide</a>). And just this month, a <a href="http://www.annfammed.org/content/17/4/352" target="_blank">study</a> showed that metformin use was associated with reduced rates of dementia and improved cognitive function among African American patients with type 2 diabetes.</strong></em>.."</p><p></p><p>Now link is US based and i get there using VPN, so you may not get in, but i'm sure the link or similar is on many other pages if you search.</p><p></p><p>Personally i kept on taking metformin once i hit normal reading, was always my intention.</p><p>as i had heard it had preventative qualities for a few things.</p><p>so this interested me.</p><p></p><p>"..</p><p><span style="font-size: 18px"><strong>7) Metformin raises cholesterol.</strong></span></p><p><em><strong>Nope! In fact, metformin has improves lipid (cholesterol) metabolism and <a href="https://care.diabetesjournals.org/content/38/10/1858" target="_blank">lowers LDL cholesterol </a>along with triglycerides.</strong></em></p><p></p><p><span style="font-size: 18px"><strong>8) Metformin is bad for the pancreas.</strong></span></p><p><strong><em>Metformin is not a known cause of acute pancreatitis and <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791389/" target="_blank">lowers</a> (not raises) the risk of pancreatic cancer.</em></strong></p><p></p><p><span style="font-size: 18px"><strong>9) Metformin causes cancer. </strong></span></p><p><strong><em>This is also not true. Metformin appears to be protective. In just one example, the <a href="https://www.ncbi.nlm.nih.gov/pubmed/22689798" target="_blank">Women’s Health Initiative</a> (WHI) found that metformin was associated with fewer cancer-related death in patients with diabetes. <a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205961/" target="_blank">Studies</a> also show that metformin may prevent colorectal polyps from returning after removal. These tiny growths in the colon can turn into cancer, which suggests that metformin may play a protective role in colon cancer.</em></strong>.."</p><p></p><p>now due diligence is required from you to check yourself,</p><p>but i'd agree the diet for dad, may not be helping.</p><p>BUT the Met may well have other benefits for a man in his Mid 70's.</p><p></p><p>However..and i know this isn't popular.</p><p>life has to have some joy, and at 76, will T2D diabetes have the time or impact it would have at 50 or 60</p><p>to do such damage as to seriously impact his life, given expectancy will be lower ?</p><p>Sorry if that's too blunt, not intended to hurt.</p><p></p><p>Not saying we shouldn't keep an eye on our elders</p><p>but we have to be reasonable, the effort of LCHF V the Enjoyment of foods we like</p><p>is an important one.</p><p></p><p>I guess it sums it it, by saying would any of us want to increase our lives, by being perfect angels right now until we die.</p><p>knowing that those last few years may well be as infirm, incontinent, & perhaps in our own brain fog, just because of our increased age. ?</p><p></p><p></p><p>Sensible about foods, yes..</p><p>religious about it...no, not for me.</p><p></p><p>i for one, would happily trade a fistfull of memories and living RIGHT now,</p><p>and for many years to come, then forgo all the Joy in life in the hope i live to 120+</p><p></p><p>These are calls we'll all have to make for our parents and for ourselves, at some point.</p><p></p><p>best of luck looking after dad.</p><p>Hope you found a way forward that suits you both.</p></blockquote><p></p>
[QUOTE="jjraak, post: 2107317, member: 493719"] Hi [USER=492004]@IronLioness[/USER] sorry hear dad is causing you worries. may well be just getting older...hope it is. watched my mum slowly slip into alzheimer's/senile dementia..awful so good your keeping an eye on him. My OH her father is similar, we can't tell him, he thinks it's a game. But he eats very sparingly, so the impact may be less then expected. Have looked before when this has come up, and i suppose it does make sense. if diabetes can cause neuropathy due to damage to nerve endings, how do we think the brain works..? But does it mean its a definite..no. i did a quick Dr google and found a US site, that suggests as do many others i'd wager that XYZ is the case. So let me just quote the part is read and leave the link to source. [URL]https://www.goodrx.com/blog/ten-myths-about-metformin/[/URL] "... [SIZE=5][B]4) Metformin causes dementia.[/B][/SIZE] [I][B]No. In fact, a recent [URL='http://www.neurologyadvisor.com/neurodegenerative-diseases/dementia-risk-reduced-metformin-type-2-diabetes/article/703995/']study[/URL] of 17,000 veterans with diabetes found that taking metformin was associated with a lower risk of dementia than other diabetes drugs known as sulfonylureas (like [URL='https://www.goodrx.com/glyburide']glyburide[/URL] and [URL='https://www.goodrx.com/glipizide']glipizide[/URL]). And just this month, a [URL='http://www.annfammed.org/content/17/4/352']study[/URL] showed that metformin use was associated with reduced rates of dementia and improved cognitive function among African American patients with type 2 diabetes.[/B][/I].." Now link is US based and i get there using VPN, so you may not get in, but i'm sure the link or similar is on many other pages if you search. Personally i kept on taking metformin once i hit normal reading, was always my intention. as i had heard it had preventative qualities for a few things. so this interested me. ".. [SIZE=5][B]7) Metformin raises cholesterol.[/B][/SIZE] [I][B]Nope! In fact, metformin has improves lipid (cholesterol) metabolism and [URL='https://care.diabetesjournals.org/content/38/10/1858']lowers LDL cholesterol [/URL]along with triglycerides.[/B][/I] [SIZE=5][B]8) Metformin is bad for the pancreas.[/B][/SIZE] [B][I]Metformin is not a known cause of acute pancreatitis and [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5791389/']lowers[/URL] (not raises) the risk of pancreatic cancer.[/I][/B] [SIZE=5][B]9) Metformin causes cancer. [/B][/SIZE] [B][I]This is also not true. Metformin appears to be protective. In just one example, the [URL='https://www.ncbi.nlm.nih.gov/pubmed/22689798']Women’s Health Initiative[/URL] (WHI) found that metformin was associated with fewer cancer-related death in patients with diabetes. [URL='https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6205961/']Studies[/URL] also show that metformin may prevent colorectal polyps from returning after removal. These tiny growths in the colon can turn into cancer, which suggests that metformin may play a protective role in colon cancer.[/I][/B].." now due diligence is required from you to check yourself, but i'd agree the diet for dad, may not be helping. BUT the Met may well have other benefits for a man in his Mid 70's. However..and i know this isn't popular. life has to have some joy, and at 76, will T2D diabetes have the time or impact it would have at 50 or 60 to do such damage as to seriously impact his life, given expectancy will be lower ? Sorry if that's too blunt, not intended to hurt. Not saying we shouldn't keep an eye on our elders but we have to be reasonable, the effort of LCHF V the Enjoyment of foods we like is an important one. I guess it sums it it, by saying would any of us want to increase our lives, by being perfect angels right now until we die. knowing that those last few years may well be as infirm, incontinent, & perhaps in our own brain fog, just because of our increased age. ? Sensible about foods, yes.. religious about it...no, not for me. i for one, would happily trade a fistfull of memories and living RIGHT now, and for many years to come, then forgo all the Joy in life in the hope i live to 120+ These are calls we'll all have to make for our parents and for ourselves, at some point. best of luck looking after dad. Hope you found a way forward that suits you both. [/QUOTE]
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