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Message: <blockquote data-quote="AlcalaBob" data-source="post: 1685502" data-attributes="member: 30529">I really think you are absolutely right to be skeptical, especially about scientific claims. It's the only healthy attitude to these things. And I think you're right, that the ND trial success was around 46% of his sample of patients. It's hard to generalise across a population without large-scale trials and even then there'd have to be caveats.  In terms of success though, given that us T2s are told we'll never overcome the condition, that it will inevitably worsen, that we will end up with secondary complications, showing that a sizeable group of patients can see the condition reversed and even disappear is, to me, a resounding success. Universal? No, not yet, but Taylor has identified the mechanisms, and demonstrated an effective treatment in close to half of patients provided they can stick to the protocol. That alone ought to get him a Nobel Prize.I'm a hardened skeptic, scientifically trained and also with a lot of years of studying scientific methodology and the philosophy of science, but I'm also a T2 who was told simply to accept it and just take the pills, so naturally I come to these things with relatively low expectations. I've been through the diabetic mill but I have to say, Taylor's work is the first that I have come across with clearly justified grounds for optimism. And my experience so far has confirmed that. There are lots of clinical studies pointing in the same direction, but Taylor gives the biochemical reasons, as Fung acknowledges. I'm sure there will be other approaches consistent with the twin cycles hypothesis, that produce the same or similar effects and that will give rise to a range of treatment regimes converging on the fat reduction. It looks like the long-term outcomes, once the diabetes is overcome, are very much determined by life-style choices and control of our own food intake and that's not really down to the ND or any specific diet. I tend to think of the ND now as just one way to take the necessary step to getting diabetes under control and in reversal.It's true that I am very determined to get the results but I think that's because of years and years of serious consistent attempts at various diets and medications which have failed. It inevitably left me despondent, angry, frustrated, but also determined to pursue it.  I haven't failed to follow instructions, or dropped out, or cheated, or stuff like that. These approaches have simply failed for me. I now see that they had little or no chance of success because they were based on an inadequate understanding of the science of diabetes - they were largely addressing consequences and not causes, and not even those effectively. On the one hand, nothing previously had worked, and on the other, this was very solid science from Taylor. And it's clearly working so far for me.  It's not yet the complete answer but I think we'll now see a lot of collaborations and an opening up of the science. It should get public funding because no pharmaceutical corporation will want to turn off the money tap of diabetes medications.I think you should remain skeptical. Skeptics are absolutely vital to helping us make sense of all this stuff.</blockquote>

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