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Dr. Malcom Kendrick On Saturated Fat
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<blockquote data-quote="LittleGreyCat" data-source="post: 1827284" data-attributes="member: 6467"><p><a href="https://drmalcolmkendrick.org/2018/07/03/why-saturated-fat-cannot-raise-cholesterol-levels-ldl-levels/" target="_blank">https://drmalcolmkendrick.org/2018/07/03/why-saturated-fat-cannot-raise-cholesterol-levels-ldl-levels/</a></p><p></p><p>Giving the establishment a righteous shoeing for not acting on the latest science, but sticking to the "old ways".</p><p></p><p>A long read but rewarding.</p><p></p><p>"</p><p>So, I am going to try and explain to you that saturated fat cannot raise blood cholesterol levels. By which I mean low density lipoprotein levels (LDLs) as this is the substance which someone or another ended up calling ‘bad’ cholesterol. It is the lipoprotein that is thought to cause CVD.</p><p>However, LDL is not cholesterol, it never was. We do not have a blood cholesterol level – but we are seemingly stuck with this hopelessly inaccurate terminology for all time.</p><p>"</p><p>"</p><p>In 1997 Keys wrote this:</p><p><em>"There's no connection whatsoever between cholesterol in food and cholesterol in blood. And we've known that all along. Cholesterol in the diet doesn't matter at all unless you happen to be a chicken or a rabbit." </em>Ancel Keys, Ph.D., professor emeritus at the University of Minnesota 1997.</p><p>"</p><p></p><p>"Just to re-cap. Saturated fat (any fat) is absorbed from the gut and packed into chylomicrons. These travel around the body, losing fat, and shrink down to a chylomicron remnant – which is then absorbed by the liver. There is no connection between chylomicrons and LDL."</p><p></p><p>"To simplify this as much as possible. If you eat more carbohydrates than your body needs, or can store, the liver converts the excess (primarily fructose and glucose) into fat in the liver. This process is called de novo lipogenesis (DNL) The fats that are synthesized are saturated fats, and only saturated fats. Once synthesized they are then packed into VLDLs and sent out of the liver."</p><p></p><p>There is loads more, but the last quote here is a key one. My understanding is that "de novo" lipogenesis is the creation of new fat from non-fats (in this case carbohydrate) and is not the repackaging of existing fat (dietary or otherwise).</p><p></p><p>So eating too much carbohydrate builds up saturated fat in the liver which is then distributed around the body.</p><p></p><p>This in turn makes me wonder where the saturated fats in our diet come from. One big source is dairy; milk, cream, butter, and of course the fat in beef. Where do the cows get the fat from? They manufacture it from their food, mainly grass in the wild, which is mainly carbohydrate. They have special adaptive gut mechanisms to enable them to release carbohydrates from the fibre. Humans don't have that mechanism which is one reason we can't survive by eating grass.</p><p></p><p>So saturated fat in grazing animals is manufactured from carbohydrate. It seems the same applies to omnivores such as ourselves.</p></blockquote><p></p>
[QUOTE="LittleGreyCat, post: 1827284, member: 6467"] [URL]https://drmalcolmkendrick.org/2018/07/03/why-saturated-fat-cannot-raise-cholesterol-levels-ldl-levels/[/URL] Giving the establishment a righteous shoeing for not acting on the latest science, but sticking to the "old ways". A long read but rewarding. " So, I am going to try and explain to you that saturated fat cannot raise blood cholesterol levels. By which I mean low density lipoprotein levels (LDLs) as this is the substance which someone or another ended up calling ‘bad’ cholesterol. It is the lipoprotein that is thought to cause CVD. However, LDL is not cholesterol, it never was. We do not have a blood cholesterol level – but we are seemingly stuck with this hopelessly inaccurate terminology for all time. " " In 1997 Keys wrote this: [I]"There's no connection whatsoever between cholesterol in food and cholesterol in blood. And we've known that all along. Cholesterol in the diet doesn't matter at all unless you happen to be a chicken or a rabbit." [/I]Ancel Keys, Ph.D., professor emeritus at the University of Minnesota 1997. " "Just to re-cap. Saturated fat (any fat) is absorbed from the gut and packed into chylomicrons. These travel around the body, losing fat, and shrink down to a chylomicron remnant – which is then absorbed by the liver. There is no connection between chylomicrons and LDL." "To simplify this as much as possible. If you eat more carbohydrates than your body needs, or can store, the liver converts the excess (primarily fructose and glucose) into fat in the liver. This process is called de novo lipogenesis (DNL) The fats that are synthesized are saturated fats, and only saturated fats. Once synthesized they are then packed into VLDLs and sent out of the liver." There is loads more, but the last quote here is a key one. My understanding is that "de novo" lipogenesis is the creation of new fat from non-fats (in this case carbohydrate) and is not the repackaging of existing fat (dietary or otherwise). So eating too much carbohydrate builds up saturated fat in the liver which is then distributed around the body. This in turn makes me wonder where the saturated fats in our diet come from. One big source is dairy; milk, cream, butter, and of course the fat in beef. Where do the cows get the fat from? They manufacture it from their food, mainly grass in the wild, which is mainly carbohydrate. They have special adaptive gut mechanisms to enable them to release carbohydrates from the fibre. Humans don't have that mechanism which is one reason we can't survive by eating grass. So saturated fat in grazing animals is manufactured from carbohydrate. It seems the same applies to omnivores such as ourselves. [/QUOTE]
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