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Ear wax monitoring vs Hba1c
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<blockquote data-quote="LittleGreyCat" data-source="post: 2346087" data-attributes="member: 6467"><p>I'm not saying that it is not interesting; it is a fascinating alternative method of measuring long term BG, and although it was not addressed in the paper (at least at the point when my brain melted) it does seem to potentially avoid the uncertainty with HbA1c where it is weighted to the last few weeks and is reliant on a normal replacement rate of red blood cells.</p><p></p><p>However we don't know if the glucose in the ear wax is denatured over time.</p><p>One of the strongest points is that if the ear is syringed then you know exactly how far back the reading goes.</p><p></p><p>One of the weakest points is that you still need a phlebotomist for all the other blood tests, and have to train someone to syringe the ear and then collect the wax sample as an additional exercise 4 weeks later.</p><p></p><p>HbA1c can be done every 6 months or a year with only one visit.</p><p>With ear wax you require 2 visits (syringe then collect 4 weeks later) or you need a much longer term study to test the effectiveness if the ear hasn't been syringed for 6 months or a year.</p><p>Also not good for initial diagnosis.</p><p></p><p>At first pass it looks as though they will have to demonstrate major clinical benefits to justify the extra training and work plus extra visits to syringe then test.</p><p></p><p>Edit: cynical me sees this as an attempt to flog the specialised collecting device for loads of money.</p></blockquote><p></p>
[QUOTE="LittleGreyCat, post: 2346087, member: 6467"] I'm not saying that it is not interesting; it is a fascinating alternative method of measuring long term BG, and although it was not addressed in the paper (at least at the point when my brain melted) it does seem to potentially avoid the uncertainty with HbA1c where it is weighted to the last few weeks and is reliant on a normal replacement rate of red blood cells. However we don't know if the glucose in the ear wax is denatured over time. One of the strongest points is that if the ear is syringed then you know exactly how far back the reading goes. One of the weakest points is that you still need a phlebotomist for all the other blood tests, and have to train someone to syringe the ear and then collect the wax sample as an additional exercise 4 weeks later. HbA1c can be done every 6 months or a year with only one visit. With ear wax you require 2 visits (syringe then collect 4 weeks later) or you need a much longer term study to test the effectiveness if the ear hasn't been syringed for 6 months or a year. Also not good for initial diagnosis. At first pass it looks as though they will have to demonstrate major clinical benefits to justify the extra training and work plus extra visits to syringe then test. Edit: cynical me sees this as an attempt to flog the specialised collecting device for loads of money. [/QUOTE]
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