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Eating Saturated Fat doesn't increase fats in blood
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<blockquote data-quote="jack412" data-source="post: 686198" data-attributes="member: 97664"><p>don't thank me..I'd take a very low dose <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite1" alt=":)" title="Smile :)" loading="lazy" data-shortname=":)" /></p><p><a href="https://www.google.com.au/#q=statin+microvascular+inflammation" target="_blank">https://www.google.com.au/#q=statin microvascular inflammation</a></p><p></p><p><a href="http://cpr.sagepub.com/content/21/4/464.full.pdf" target="_blank">http://cpr.sagepub.com/content/21/4/464.full.pdf</a></p><p></p><p>Results: Among 14 primary prevention trials (46,262 participants),</p><p></p><p>statin therapy increased diabetes by absolute risk of 0.5% (95% CI 0.1–1%, p¼0.012),</p><p></p><p>meanwhile reducing death by a similar extent: 0.5% (0.9 to 0.2%, p¼0.003).</p><p></p><p>In the 15 secondary prevention RCTs (37,618 participants), statins decreased death by 1.4% (2.1 to 0.7%, p<0.001).</p><p></p><p>There were no other statin-attributable symptoms,</p><p></p><p>although asymptomatic liver transaminase elevation was 0.4% more frequent with statins across all trials. Serious adverse events and withdrawals were similar in both arms.</p><p></p><p></p><p>Conclusions:</p><p></p><p>Only a small minority of symptoms reported on statins are genuinely due to the statins:</p><p></p><p></p><p>almost all would occur just as frequently on placebo.</p><p></p><p></p><p>Only development of new-onset diabetes mellitus was significantly higher on statins than placebo; nevertheless only 1 in 5 of new cases were actually caused by statins. Higher statin doses produce a detectable effect, but even still the proportion attributable to statins is variable: for asymptomatic liver enzyme elevation, the majority are attributable to the higher dose; in contrast for muscle aches, the majority are not.</p><p></p><p></p><p>this study looked at the history of 60,000 Diabetics after av. 2.7</p><p></p><p><a href="http://www.thelancet.com/journals/landia/article/PIIS2213-8587(14)70173-1/abstract" target="_blank">http://www.thelancet.com/journals/landia/article/PIIS2213-8587(14)70173-1/abstract</a></p><p></p><p>retinopathy HR=0.6 [decrease of risk]</p><p></p><p>neuropathy HR=0.66</p><p></p><p>gangrene of the foot HR=0.88</p><p></p><p>diabetic nephropathy HR=0.97</p><p></p><p>[neutral..........HR=1.0 ]</p><p></p><p>diabetes HR=1·17 [increase of risk]</p><p></p><p></p><p></p><p>the way I look at it ..if nothing else take statin for neuropathy, retinopathy and gangrene of the foot</p></blockquote><p></p>
[QUOTE="jack412, post: 686198, member: 97664"] don't thank me..I'd take a very low dose :) [URL='https://www.google.com.au/#q=statin+microvascular+inflammation']https://www.google.com.au/#q=statin microvascular inflammation[/URL] [url]http://cpr.sagepub.com/content/21/4/464.full.pdf[/url] Results: Among 14 primary prevention trials (46,262 participants), statin therapy increased diabetes by absolute risk of 0.5% (95% CI 0.1–1%, p¼0.012), meanwhile reducing death by a similar extent: 0.5% (0.9 to 0.2%, p¼0.003). In the 15 secondary prevention RCTs (37,618 participants), statins decreased death by 1.4% (2.1 to 0.7%, p<0.001). There were no other statin-attributable symptoms, although asymptomatic liver transaminase elevation was 0.4% more frequent with statins across all trials. Serious adverse events and withdrawals were similar in both arms. Conclusions: Only a small minority of symptoms reported on statins are genuinely due to the statins: almost all would occur just as frequently on placebo. Only development of new-onset diabetes mellitus was significantly higher on statins than placebo; nevertheless only 1 in 5 of new cases were actually caused by statins. Higher statin doses produce a detectable effect, but even still the proportion attributable to statins is variable: for asymptomatic liver enzyme elevation, the majority are attributable to the higher dose; in contrast for muscle aches, the majority are not. this study looked at the history of 60,000 Diabetics after av. 2.7 [url]http://www.thelancet.com/journals/landia/article/PIIS2213-8587(14)70173-1/abstract[/url] retinopathy HR=0.6 [decrease of risk] neuropathy HR=0.66 gangrene of the foot HR=0.88 diabetic nephropathy HR=0.97 [neutral..........HR=1.0 ] diabetes HR=1·17 [increase of risk] the way I look at it ..if nothing else take statin for neuropathy, retinopathy and gangrene of the foot [/QUOTE]
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