In my darkest moments, and there have been plenty, I find some solace in various 'skyhooks' as I call them. Anything from experiences of persisting against what appeared to be impossible odds; the way another has managed the burden of despair; the ebullient enthusiasm of my daughter with Down Syndrome; having a hobby which allows creativity (even as I pull hair out sometimes with frustration); the use of self-humour to stop taking myself too seriously.
For me all this gelled when I read about Thomas Szasz, a concentration camp survivor and psychiatrist.
If life, suffering, experience has some meaning, it becomes more bearable.