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Type 1 Diabetes
Exogenous Insulin question.
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<blockquote data-quote="Art Of Flowers" data-source="post: 1649431" data-attributes="member: 375067"><p>High glucose levels and high insulin levels are toxic and are the primary reasons why people with diabetes have shorter life expectancy. With type 2 diabetes there is typically insulin resistance which leads to high insulin levels being needed to process blood glucose. Treating type 2 with insulin or drugs which stimulate insulin resistance further exacerbates the high levels of insulin and can lead to increased all cause mortality despite lowering blood glucose. There is a "J" risk curve for mortality for type 2 diabetes treated with insulin with both high and low blood glucose being at high risk with the minimum risk having a HbA1C around 7.5%. The increased risk at lower average blood sugars is due to insulin toxicity. Jason Fung describes this in his online videos.</p><p></p><p>Insulin does cause excess blood glucose to be stored as fat. People with type 1 diabetes can get insulin resistance also. This is known as Double Diabetes.</p></blockquote><p></p>
[QUOTE="Art Of Flowers, post: 1649431, member: 375067"] High glucose levels and high insulin levels are toxic and are the primary reasons why people with diabetes have shorter life expectancy. With type 2 diabetes there is typically insulin resistance which leads to high insulin levels being needed to process blood glucose. Treating type 2 with insulin or drugs which stimulate insulin resistance further exacerbates the high levels of insulin and can lead to increased all cause mortality despite lowering blood glucose. There is a "J" risk curve for mortality for type 2 diabetes treated with insulin with both high and low blood glucose being at high risk with the minimum risk having a HbA1C around 7.5%. The increased risk at lower average blood sugars is due to insulin toxicity. Jason Fung describes this in his online videos. Insulin does cause excess blood glucose to be stored as fat. People with type 1 diabetes can get insulin resistance also. This is known as Double Diabetes. [/QUOTE]
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