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<blockquote data-quote="jddukes" data-source="post: 681880" data-attributes="member: 49946"><p>Hi Emmotha,</p><p></p><p>This is why I am finding it hard to accept the notion that your body gets "used to the sensor" based on the reason given for the first day of settling.</p><p></p><p>If the reason is due to increased fluid to the site due to inflammation (the mechanism makes perfect sense) thus diluting the interstitial fluid and giving a false-low reading, then when you put another sensor on the other arm (a completely new site) you should see the same effect.</p><p></p><p>Perhaps you were lucky, perhaps it is not the actual reason why the readings are low, perhaps it is more batch variation or just bodily variation and the degree of inflammation, but it doesn't sit right with me and the biology of your body that putting on one arm "conditions" your body to not give the same response in a completely different location.</p><p></p><p>This is why I am thinking about for the next application I do, of putting it on 24hrs prior to activation regardless.</p><p></p><p>BTW - people complaining about the needle - the needle is bigger than a standard insulin needle yes, but how else do you get the filament on? To claim the positive reviews are Abbot's PR and the needle is totally unexpected are frankly silly and naive. Yet it is quite different to a insulin needle as it is put in a quite insensitive place but also it is a jabbing motion, very rapid, to inject the filament, then the needle retracts. I experienced no pain whatsoever with it, personally. I do think it is unfair to say because there is a needle there the whole thing is a con!</p><p></p><p>Also it may be worth pointing out that as these are factory calibrated, there may be more risk to false readings if you choose a different location. Why? Because there is a very good reason to suspect the formula/calculation the machine must do to try and convert interstitial fluid levels to appropriate blood levels may vary depending on location of interstitial fluid, and/or the time lag may differ. Maybe not, but at least with other systems you calibrate to blood so this is less of a concern.</p><p></p><p>J</p></blockquote><p></p>
[QUOTE="jddukes, post: 681880, member: 49946"] Hi Emmotha, This is why I am finding it hard to accept the notion that your body gets "used to the sensor" based on the reason given for the first day of settling. If the reason is due to increased fluid to the site due to inflammation (the mechanism makes perfect sense) thus diluting the interstitial fluid and giving a false-low reading, then when you put another sensor on the other arm (a completely new site) you should see the same effect. Perhaps you were lucky, perhaps it is not the actual reason why the readings are low, perhaps it is more batch variation or just bodily variation and the degree of inflammation, but it doesn't sit right with me and the biology of your body that putting on one arm "conditions" your body to not give the same response in a completely different location. This is why I am thinking about for the next application I do, of putting it on 24hrs prior to activation regardless. BTW - people complaining about the needle - the needle is bigger than a standard insulin needle yes, but how else do you get the filament on? To claim the positive reviews are Abbot's PR and the needle is totally unexpected are frankly silly and naive. Yet it is quite different to a insulin needle as it is put in a quite insensitive place but also it is a jabbing motion, very rapid, to inject the filament, then the needle retracts. I experienced no pain whatsoever with it, personally. I do think it is unfair to say because there is a needle there the whole thing is a con! Also it may be worth pointing out that as these are factory calibrated, there may be more risk to false readings if you choose a different location. Why? Because there is a very good reason to suspect the formula/calculation the machine must do to try and convert interstitial fluid levels to appropriate blood levels may vary depending on location of interstitial fluid, and/or the time lag may differ. Maybe not, but at least with other systems you calibrate to blood so this is less of a concern. J [/QUOTE]
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