Search
Search titles only
By:
Search titles only
By:
Home
Forums
New posts
Search forums
What's new
New posts
New profile posts
Latest activity
Members
Current visitors
New profile posts
Search profile posts
Log in
Register
Search
Search titles only
By:
Search titles only
By:
New posts
Search forums
Menu
Install the app
Install
Reply to Thread
Guest, we'd love to know what you think about the forum! Take the
Diabetes Forum Survey 2024 »
Home
Forums
Diabetes Discussion
Type 1 Diabetes
Freestyle Libre - worth every penny
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Message
<blockquote data-quote="Scott-C" data-source="post: 1579834" data-attributes="member: 374531"><p>Libre seems to work very well with some people, much less so with others.</p><p></p><p>We're putting the sensor filament into a hostile environment, the immune system attacks it because it shouldn't be there (mind you, it also attacked our beta cells which should be there, maybe those guys should be invited in by HR for a performance review...), it gets "biofouled" or clagged up with protein, cells get trapped up in that which eat glucose so it can't then be measured by the sensor because it's already been eaten before it gets anywhere near the sensor.</p><p></p><p>It's amazing that these things work at all. The papers I've read are way above the little I remember from O grade and Higher chemistry/biology 3 decades ago, but I wonder whether some people's particular body chemistry/immune system responses/random unknown factor just makes it more difficult for the sensor to do its job compared to others, hence some get decent readings and others get flyers.</p><p></p><p>There's a lengthy article in link below dealing with the crazy complexities going on when you're trying to find out what bg is from measuring interstitial fluid glucose. Maybe those complexities just tank it for some people's individual chemistry, but not for others.</p><p></p><p><a href="https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903977/" target="_blank">https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903977/</a></p></blockquote><p></p>
[QUOTE="Scott-C, post: 1579834, member: 374531"] Libre seems to work very well with some people, much less so with others. We're putting the sensor filament into a hostile environment, the immune system attacks it because it shouldn't be there (mind you, it also attacked our beta cells which should be there, maybe those guys should be invited in by HR for a performance review...), it gets "biofouled" or clagged up with protein, cells get trapped up in that which eat glucose so it can't then be measured by the sensor because it's already been eaten before it gets anywhere near the sensor. It's amazing that these things work at all. The papers I've read are way above the little I remember from O grade and Higher chemistry/biology 3 decades ago, but I wonder whether some people's particular body chemistry/immune system responses/random unknown factor just makes it more difficult for the sensor to do its job compared to others, hence some get decent readings and others get flyers. There's a lengthy article in link below dealing with the crazy complexities going on when you're trying to find out what bg is from measuring interstitial fluid glucose. Maybe those complexities just tank it for some people's individual chemistry, but not for others. [URL]https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2903977/[/URL] [/QUOTE]
Verification
Post Reply
Home
Forums
Diabetes Discussion
Type 1 Diabetes
Freestyle Libre - worth every penny
Top
Bottom
Find support, ask questions and share your experiences. Ad free.
Join the community »
This site uses cookies. By continuing to use this site, you are agreeing to our use of cookies.
Accept
Learn More.…