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Gck Mody
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<blockquote data-quote="phoenix" data-source="post: 1824919" data-attributes="member: 12578"><p>According to specialists, Gck MODY doesn't normally benefit from treatment. The fault is that the mechanism that detects higher glucose and initiates the release of insulin is set a bit higher than normal.Your body will try to maintain that level which is 'normal' for it. It is very unusual for someone with this type of diabetes to develop serious complications, even after many years with persistently raised fasting levels. The problem will have been present since birth but diagnosis often only happens after routine testing. (so many people have it for decades before diagnosis)</p><p><a href="https://www.diapedia.org/other-types-of-diabetes-mellitus/41040851237/mody-due-to-glucokinase-mutations" target="_blank">https://www.diapedia.org/other-types-of-diabetes-mellitus/41040851237/mody-due-to-glucokinase-mutations</a></p><p></p><p>Nevertheless, a person with Gck MODY is not immune to developing insulin resistance " It is possible for an individual with a change in the <em>GCK</em> gene to develop other types of diabetes that require treatment. Patients have the same risk of developing Type 2 diabetes as other members of the general population. Type 2 diabetes is common in older people especially if they are overweight and can need tablet or insulin treatment."://<a href="http://www.diabetesgenes.org/what-is-mody/what-is-glucokinase-gck/" target="_blank">www.diabetesgenes.org/what-is-mody/what-is-glucokinase-gck/</a></p><p>So you need to get your GP to explain his rationale for suggesting Met and if possible ask the specialist if he agrees.</p></blockquote><p></p>
[QUOTE="phoenix, post: 1824919, member: 12578"] According to specialists, Gck MODY doesn't normally benefit from treatment. The fault is that the mechanism that detects higher glucose and initiates the release of insulin is set a bit higher than normal.Your body will try to maintain that level which is 'normal' for it. It is very unusual for someone with this type of diabetes to develop serious complications, even after many years with persistently raised fasting levels. The problem will have been present since birth but diagnosis often only happens after routine testing. (so many people have it for decades before diagnosis) [URL]https://www.diapedia.org/other-types-of-diabetes-mellitus/41040851237/mody-due-to-glucokinase-mutations[/URL] Nevertheless, a person with Gck MODY is not immune to developing insulin resistance " It is possible for an individual with a change in the [I]GCK[/I] gene to develop other types of diabetes that require treatment. Patients have the same risk of developing Type 2 diabetes as other members of the general population. Type 2 diabetes is common in older people especially if they are overweight and can need tablet or insulin treatment."://[URL='http://www.diabetesgenes.org/what-is-mody/what-is-glucokinase-gck/']www.diabetesgenes.org/what-is-mody/what-is-glucokinase-gck/[/URL] So you need to get your GP to explain his rationale for suggesting Met and if possible ask the specialist if he agrees. [/QUOTE]
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