Patch said:I'm on 80mg of gliclazide once a day. Used to take Met SR too, but decided to stop because of the side effects.
80mg is only a quarter of what you can take. Max dose is 320mg daily.
What other treatment can be used in conjunction with Gliclazide? I've got high Trigs (5.1), so Byetta and Victoza are out of the question.
Don't know why the Trigs level has anything to do with you not getting Byetta or Victoza as they are both bg lowering drugs.
The Dr. wants to put me on over night insulin, but I've refused so far because I can't afford to put any weight on.
Gliclizide can have the effect of making you gain weight especially in higher doses.
Is anybody combining Gliclazide with any other oral medicines to lower/control BG?
Inflammation of the pancreas (pancreatitis) may be severe and lead to death. Certain medical conditions make you more likely to get pancreatitis. Therefore before taking Victoza, tell your healthcare provider if you have had pancreatitis, stones in your gallbladder (gallstones), a history of alcoholism, or high blood triglyceride levels.
Patch said:Sue - I specifically asked my doctor about the Gliclazide doses, and he said that 80mg was the max. I'll speak to him again shortly.
Dose
Initially, 40–80 mg daily, adjusted according to response; up to 160 mg as a single dose, with breakfast; higher doses divided; max. 320 mg daily
It's not clear if Byetta caused the 30 reported cases of acute pancreatitis.
Most of those patients -- 27 out of 30 -- had other risk factors for acute pancreatitis, including gallstones, alcohol use, and severe hypertriglyceridemia (extremely high levels of triglycerides)
Twenty-two of the patients improved after discontinuing Byetta. Symptoms of acute pancreatitis returned when three of the patients started using Byetta again, according to the FDA.
Hypertriglyceridemia is a risk factor for pancreatitis and it accounts for 1 to 4% of cases of acute pancreatitis. Although a few patients can develop pancreatitis with triglyceride levels >500 mg/dL, the risk for pancreatitis does not become clinically significant until levels are >1000 mg/dL.[1,4,5] More importantly however, hypertriglyceridemia is typically not an isolated abnormality. It is frequently associated with other lipid abnormalities and the metabolic syndrome (abdominal obesity, insulin resistance, low high-density lipoprotein (HDL), high triglyceride, and hypertension), which are linked to coronary artery disease.
Patch wrote, "Can you point me in the direction of any documentation that states high trigs doesn't effect the use of Byetta/victoza? The information I have read states that elevated trigs put Byetta & Victoza users at higher risk of Pancreatic Cancer, Pancreatitis and other diseases of the Pancreas.
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