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Message: <blockquote data-quote="EllieM" data-source="post: 1946656" data-attributes="member: 372717">My 88 year old Dad has been T2 for about 10 years, last couple on gliclazide instead of metformin.  He's always been told that T2s don't need to test but recently visited hospital for suspected heart attack after chest pains and came out with a meter and instructions to blood test.  Of course, they did not tell him when they wanted him to test and he decided to leave it all for a couple of months till his annual 3 month visit to me (T1 daughter) in NZ.Recent HbA1C is 54, which isn't outrageous and honestly, given his age, not something I would worry about too much.  But he also wanted to lose some weight so going lower carb seems like a good idea and before arriving here he's given up on the potatoes and bread and had lost a small amount of weight (or at least waist line). So, we're doing blood tests, mostly before meals but will move to some after meals to check how bad certain foods are.  Lowest we've got is 5.5 and highest is 9, but they've drifted a bit lower on the slightly lower carb diet here compared to his home. I've only done one after meal test, and that was less than 2 above the pre-meal result, so I was pretty pleased.My main question is does anyone know the time profile of gliclazide?  I know it increases insulin production but not whether it's a 24 hour thing or a few hour thing - the nurse told him he could take 2 in morning and 1 at night (because that's when he takes his other pills) and he's tending to take his two at 7am, before getting up and breakfasting at 9am.  So his relatively low before breakfast readings come two hours after taking the gliclazide.  Now, as a T1,  there's no way that I'd take bolus insulin 2 hours before breakfast but am assuming that gliclazide is more like a basal insulin?????Help please.</blockquote>

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