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Message: <blockquote data-quote="lovinglife" data-source="post: 2669010" data-attributes="member: 22428">When I was on Gliclizide twice a day I used to take it before breakfast and before my evening meal, the important thing to remember is that the optimum time to take gliclizide is 20minutes before you eat your meal as it triggers insulin release and can cause hypos if you don’t eat. Also as your dose has been doubled I would also watch out for hypos after eating too just to make sure you aren’t going too low. If you find yourself having regular hypos you may need either to up your carbs or do what I did and with the support of your GP reduce your dose If on occasion I didn’t eat breakfast I used to have it before my lunch and dinner. But I never ate between meals and my meals were 6-7 hrs apart</blockquote>

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