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<blockquote data-quote="Steve57" data-source="post: 93377" data-attributes="member: 21737"><p>Hi Everyone</p><p></p><p> I was diagnosed T2 five years ago when fasting BG levels rose above 7. </p><p></p><p> For the last three years I have been on Metformin 850mg twice a day and Pioglitazone 30mg once a day. Hba1c has consistently been 6.1 or 6.2 during this time. </p><p></p><p> At my annual review in April this year I mentioned that I was getting fed up with stomach problems, frequent diarrhea etc. My doctor said this was the Metformin and replaced it with 80mg Gliclazide once a day. Over the following two and a half months I have been constantly tired/fatigued and have experienced a few shaky moments where my BG's have fell below 4. </p><p></p><p> I have just had another hba1c test as a follow up to the change in medication which has come back as 6. My doctor is satisfied with this result but due to the 'shaky' moments has switched me to Gliclazide 30mg M/R. When he told me this I thought he was reducing the dosage but having referred to the internet I find this is the slow release version of the previous medication. He doesn't think that the tiredness/fatigue is due to the Gliclazide which I find surprising since it started immediately after the change from Metformin. He has asked for further blood tests to see if there is another cause.</p><p></p><p> Has anyone else had similar problems with Gliclazide??</p><p></p><p></p><p> Thanks</p><p></p><p> Steve</p></blockquote><p></p>
[QUOTE="Steve57, post: 93377, member: 21737"] Hi Everyone I was diagnosed T2 five years ago when fasting BG levels rose above 7. For the last three years I have been on Metformin 850mg twice a day and Pioglitazone 30mg once a day. Hba1c has consistently been 6.1 or 6.2 during this time. At my annual review in April this year I mentioned that I was getting fed up with stomach problems, frequent diarrhea etc. My doctor said this was the Metformin and replaced it with 80mg Gliclazide once a day. Over the following two and a half months I have been constantly tired/fatigued and have experienced a few shaky moments where my BG's have fell below 4. I have just had another hba1c test as a follow up to the change in medication which has come back as 6. My doctor is satisfied with this result but due to the 'shaky' moments has switched me to Gliclazide 30mg M/R. When he told me this I thought he was reducing the dosage but having referred to the internet I find this is the slow release version of the previous medication. He doesn't think that the tiredness/fatigue is due to the Gliclazide which I find surprising since it started immediately after the change from Metformin. He has asked for further blood tests to see if there is another cause. Has anyone else had similar problems with Gliclazide?? Thanks Steve [/QUOTE]
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