Search
Search titles only
By:
Search titles only
By:
Home
Forums
New posts
Search forums
What's new
New posts
New profile posts
Latest activity
Members
Current visitors
New profile posts
Search profile posts
Log in
Register
Search
Search titles only
By:
Search titles only
By:
New posts
Search forums
Menu
Install the app
Install
Reply to Thread
Guest, we'd love to know what you think about the forum! Take the
Diabetes Forum Survey 2025 »
Home
Forums
Diabetes Discussion
Diabetes Discussions
Have you cured or reversed type 2
JavaScript is disabled. For a better experience, please enable JavaScript in your browser before proceeding.
You are using an out of date browser. It may not display this or other websites correctly.
You should upgrade or use an
alternative browser
.
Message
<blockquote data-quote="Yorksman" data-source="post: 376315" data-attributes="member: 55568"><p>You will probably be aware of the Counterpoint Study, the Lim et al. paper, 2011, Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol.</p><p><a href="http://www.ncbi.nlm.nih.gov/pubmed/21656330" target="_blank">http://www.ncbi.nlm.nih.gov/pubmed/21656330</a></p><p></p><p>Much has been written about what is meant by 'reversal' with commentary ranging between good control without the need for medication to a full and complete restoration to pre diabetes level. Sadly, the loss of beta cells cannot be restored. Loss is often quoted as around 50% by the time of diagnosis. This guesstimate however is a mean and so individuals vary widely. Whilst type 2 diabetes is normally characterised by the continued decline of the beta cell function, even where good control is achieved, Lim et al maintain that the decline can be halted. When they talk about reversal, they really mean it won't inevitably get worse, not that those lost beta cells grow back. They don't. But, you won't lose anymore, which is what is meant by continued decline.</p><p></p><p>There's always a fair amount of estimation in this as the only way to be sure is to slice open the pancreas of the patient and start counting. It's only ever been done post mortem and on rats. Roy Taylor of the Magnetic Resonance Centre at Newcastle hypothesises that the islets become blocked, reducing insulin secretion and the beta cells start dying off. Dramatic weight loss seemed to unblock these islets, first noted in patient's who underwent baryatric surgery. The paper above attempted to achieve the same effect through diet.</p><p></p><p>The Mag Res centre has recently published a follow up paper: Population response to information on reversibility of Type 2 diabetes,</p><p><a href="http://www.ncl.ac.uk/magres/research/diabetes/CounterpointReflections.pdf" target="_blank">http://www.ncl.ac.uk/magres/research/di ... ctions.pdf</a></p><p></p><p>and the Mag Res centre maintains a page entitled Reversing Type 2 Diabetes at </p><p><a href="http://www.ncl.ac.uk/magres/research/diabetes/reversal.htm" target="_blank">http://www.ncl.ac.uk/magres/research/di ... versal.htm</a></p></blockquote><p></p>
[QUOTE="Yorksman, post: 376315, member: 55568"] You will probably be aware of the Counterpoint Study, the Lim et al. paper, 2011, Reversal of type 2 diabetes: normalisation of beta cell function in association with decreased pancreas and liver triacylglycerol. [url=http://www.ncbi.nlm.nih.gov/pubmed/21656330]http://www.ncbi.nlm.nih.gov/pubmed/21656330[/url] Much has been written about what is meant by 'reversal' with commentary ranging between good control without the need for medication to a full and complete restoration to pre diabetes level. Sadly, the loss of beta cells cannot be restored. Loss is often quoted as around 50% by the time of diagnosis. This guesstimate however is a mean and so individuals vary widely. Whilst type 2 diabetes is normally characterised by the continued decline of the beta cell function, even where good control is achieved, Lim et al maintain that the decline can be halted. When they talk about reversal, they really mean it won't inevitably get worse, not that those lost beta cells grow back. They don't. But, you won't lose anymore, which is what is meant by continued decline. There's always a fair amount of estimation in this as the only way to be sure is to slice open the pancreas of the patient and start counting. It's only ever been done post mortem and on rats. Roy Taylor of the Magnetic Resonance Centre at Newcastle hypothesises that the islets become blocked, reducing insulin secretion and the beta cells start dying off. Dramatic weight loss seemed to unblock these islets, first noted in patient's who underwent baryatric surgery. The paper above attempted to achieve the same effect through diet. The Mag Res centre has recently published a follow up paper: Population response to information on reversibility of Type 2 diabetes, [url=http://www.ncl.ac.uk/magres/research/diabetes/CounterpointReflections.pdf]http://www.ncl.ac.uk/magres/research/di ... ctions.pdf[/url] and the Mag Res centre maintains a page entitled Reversing Type 2 Diabetes at [url=http://www.ncl.ac.uk/magres/research/diabetes/reversal.htm]http://www.ncl.ac.uk/magres/research/di ... versal.htm[/url] [/QUOTE]
Verification
Post Reply
Home
Forums
Diabetes Discussion
Diabetes Discussions
Have you cured or reversed type 2
Top
Bottom
Find support, ask questions and share your experiences. Ad free.
Join the community »
This site uses cookies. By continuing to use this site, you are agreeing to our use of cookies.
Accept
Learn More.…
