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HbA1c and Complications
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<blockquote data-quote="Trinkwasser" data-source="post: 38639" data-attributes="member: 11875"><p>This is true, however there are many other factors involved. Blood cells are glycated reversibly at first, so a brief spike will glycate them temporarily and they will then revert. This is NOT true of some other tissues. So it may underrestimate the potential for damage in people whose BG varies a lot.</p><p></p><p>Also the degree of glycation can be affected by other factors, not least high or low turnover of cells, some individuals are may show high or low A1cs compared to their actual spot numbers.</p></blockquote><p></p>
[QUOTE="Trinkwasser, post: 38639, member: 11875"] This is true, however there are many other factors involved. Blood cells are glycated reversibly at first, so a brief spike will glycate them temporarily and they will then revert. This is NOT true of some other tissues. So it may underrestimate the potential for damage in people whose BG varies a lot. Also the degree of glycation can be affected by other factors, not least high or low turnover of cells, some individuals are may show high or low A1cs compared to their actual spot numbers. [/QUOTE]
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