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HbA1c down from 75 to 37!
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<blockquote data-quote="ianf0ster" data-source="post: 2176153" data-attributes="member: 506169"><p>[USER=345386]@DCUKMod[/USER],</p><p> I apologise for my loose use of terms. I did not mean that all the methods I outline work for all Type 2's. Just that they are all proven to work for some Type 2's - which is something that no drug can do, because all the drugs can do is to treat the symptoms.</p><p></p><p>I would consider diabetics who are Insulin Sensitive but whose pancreas doesn't produce enough Insulin for a reasonable diet to be 'Pre-Type 1 or LADA rather than Type 2 diabetics though this may not be the correct medical term. When I asked my Diabetic Specialist GP upon my diagnosis about insulin production (bearing in mind that my Insulin levels were never tested), he said I was >95% certainly Insulin Resistant. So I assumed that this would be the case for other Type 2's.</p><p></p><p></p><p>I don't have the figures at hand for the latest studies for the methods I outlined, however from recollection they are all pretty good initially. The question marks are around the edges - such as:</p><p>Which definition of 'remission' is used - HbA1C down into the pre-diabetic range or all the way down into the normal range? On zero diabetes medications or is Metformin allowed? Over how long does the lowered HbA1C need to be held before it is considered to be remission?</p><p></p><p>My understanding is that the effectiveness of the methods is not in dispute - merely the compliance rate (or in the case of Bariatric Surgery the degree of trying to 'cheat'). RCTs are pretty much impossible for lifestyle interventions, so many establishment figures will dismiss studies out of hand.</p><p></p><p>1. LC(HF): Dr Unwin's most recent figures appear to show between 40% and 50% in remission at the 2yr mark. I believe that Virta Health in the USA get even better figures, though their patients are more probably fully invested in LCHF than with Dr Unwin's more gentle casual approach.</p><p></p><p>2. Time Restricted Eating: I don't recall any stats on people who used this method exclusively, but have seen videos by medical professionals who claimed it to be as effective as Low Carb (due to the extended period of avoiding carb intake). That would make sense, since carbs too high drive high Insulin which drives body fat storage and inhibits use of body fat as fuel etc.</p><p></p><p>3. A). Dr Jason Fung's first patients were being treated for Kidney disease and Morbid Obesity rather than diabetes. In his first book he quoted only a small number of patients who were mainly from the poorer sections of society in Toronto and so couldn't afford healthy low carb vegetables. His methods are only applicable to those who have a lot of stored body fat, but it is reported both by him and many others that once past the first few days, the longer fasting becomes easier and easier as the energy levels increase. But as a TOFI I have not investigated this in depth.</p><p></p><p>B). This article in the Lancet suggests that the latest DIRECT figures show a 46% remission rate.: </p><p><a href="https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)33102-1/fulltext" target="_blank">https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)33102-1/fulltext</a></p><p>(edited to include link).</p><p></p><p>C). Bariatric surgery (I think there are 3 or more different possible procedures in use) is primarily used in the treatment of Morbid Obesity rather than Diabetes. However I recall proponents saying that the initial success rate was extremely high c 80% and that Blood Glucose drops dramatically, well before any measurable weight loss. But that the success rates fell away fairly dramatically after 6 months or 1 yr, down to similar levels reported for Low Carb lifestyle interventions.</p><p></p><p></p><p>To conclude: In my view there is no reason (other than the recalcitrance of the medical establishment) why there are not already far fewer Type 2's.</p></blockquote><p></p>
[QUOTE="ianf0ster, post: 2176153, member: 506169"] [USER=345386]@DCUKMod[/USER], I apologise for my loose use of terms. I did not mean that all the methods I outline work for all Type 2's. Just that they are all proven to work for some Type 2's - which is something that no drug can do, because all the drugs can do is to treat the symptoms. I would consider diabetics who are Insulin Sensitive but whose pancreas doesn't produce enough Insulin for a reasonable diet to be 'Pre-Type 1 or LADA rather than Type 2 diabetics though this may not be the correct medical term. When I asked my Diabetic Specialist GP upon my diagnosis about insulin production (bearing in mind that my Insulin levels were never tested), he said I was >95% certainly Insulin Resistant. So I assumed that this would be the case for other Type 2's. I don't have the figures at hand for the latest studies for the methods I outlined, however from recollection they are all pretty good initially. The question marks are around the edges - such as: Which definition of 'remission' is used - HbA1C down into the pre-diabetic range or all the way down into the normal range? On zero diabetes medications or is Metformin allowed? Over how long does the lowered HbA1C need to be held before it is considered to be remission? My understanding is that the effectiveness of the methods is not in dispute - merely the compliance rate (or in the case of Bariatric Surgery the degree of trying to 'cheat'). RCTs are pretty much impossible for lifestyle interventions, so many establishment figures will dismiss studies out of hand. 1. LC(HF): Dr Unwin's most recent figures appear to show between 40% and 50% in remission at the 2yr mark. I believe that Virta Health in the USA get even better figures, though their patients are more probably fully invested in LCHF than with Dr Unwin's more gentle casual approach. 2. Time Restricted Eating: I don't recall any stats on people who used this method exclusively, but have seen videos by medical professionals who claimed it to be as effective as Low Carb (due to the extended period of avoiding carb intake). That would make sense, since carbs too high drive high Insulin which drives body fat storage and inhibits use of body fat as fuel etc. 3. A). Dr Jason Fung's first patients were being treated for Kidney disease and Morbid Obesity rather than diabetes. In his first book he quoted only a small number of patients who were mainly from the poorer sections of society in Toronto and so couldn't afford healthy low carb vegetables. His methods are only applicable to those who have a lot of stored body fat, but it is reported both by him and many others that once past the first few days, the longer fasting becomes easier and easier as the energy levels increase. But as a TOFI I have not investigated this in depth. B). This article in the Lancet suggests that the latest DIRECT figures show a 46% remission rate.: [URL]https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)33102-1/fulltext[/URL] (edited to include link). C). Bariatric surgery (I think there are 3 or more different possible procedures in use) is primarily used in the treatment of Morbid Obesity rather than Diabetes. However I recall proponents saying that the initial success rate was extremely high c 80% and that Blood Glucose drops dramatically, well before any measurable weight loss. But that the success rates fell away fairly dramatically after 6 months or 1 yr, down to similar levels reported for Low Carb lifestyle interventions. To conclude: In my view there is no reason (other than the recalcitrance of the medical establishment) why there are not already far fewer Type 2's. [/QUOTE]
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