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HbA1c represents a 4 week average?
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<blockquote data-quote="phoenix" data-source="post: 233460" data-attributes="member: 12578"><p>Red blood cells last on average 3 months, new cells are being added all the time. There will be more newer blood cells than the oldest ones so HbA1c is weighted towards more recent levels. 4 week average??? don't know</p><p> Initially glycation is reversible but this is a temporary state.</p><p> It does appear that some people are high glycators some lower glycators, This is why 2 people who have similar averages can have very different HbA1cs. </p><p></p><p> This study from 2009, found that low glycators,ie those with lower HbA1cs than their average glucose levels would suggest, had higher levels of labile A1c (ie glycated haemoglobin that is still reversible)</p><p>They say</p><p> <a href="http://care.diabetesjournals.org/content/33/2/273.full" target="_blank">http://care.diabetesjournals.org/content/33/2/273.full</a></p><p></p><p> No-one seems to know just what causes people to be high or low glycators (biological variation?) but it may influence outcomes. </p><p></p><p>edited, put in some punctuation!</p><p> .</p></blockquote><p></p>
[QUOTE="phoenix, post: 233460, member: 12578"] Red blood cells last on average 3 months, new cells are being added all the time. There will be more newer blood cells than the oldest ones so HbA1c is weighted towards more recent levels. 4 week average??? don't know Initially glycation is reversible but this is a temporary state. It does appear that some people are high glycators some lower glycators, This is why 2 people who have similar averages can have very different HbA1cs. This study from 2009, found that low glycators,ie those with lower HbA1cs than their average glucose levels would suggest, had higher levels of labile A1c (ie glycated haemoglobin that is still reversible) They say [url=http://care.diabetesjournals.org/content/33/2/273.full]http://care.diabetesjournals.org/content/33/2/273.full[/url] No-one seems to know just what causes people to be high or low glycators (biological variation?) but it may influence outcomes. edited, put in some punctuation! . [/QUOTE]
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