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<blockquote data-quote="TheBigNewt" data-source="post: 1486085" data-attributes="member: 380756"><p>The study was stopped after 3.7 years, so it's not like it didn't go on for awhile. The point is the premise going in was that the outcome would be better in the intensively treated group (avg A1C=6.6) vs the "standard" group (A1C=7.7). The A1C was 8.3 in both groups at the start. These people all had diabetes for at least 10 years and weighed about 93kg, so they were a higher risk group for sure. Fewer heart attacks but more cardiovascular deaths in the intensive group, who took more diabetes drugs on the average. Not what they expected at all. Their LDL cholesterol was around 90 in both groups and didn't change, so I'm sure most were on statins.</p></blockquote><p></p>
[QUOTE="TheBigNewt, post: 1486085, member: 380756"] The study was stopped after 3.7 years, so it's not like it didn't go on for awhile. The point is the premise going in was that the outcome would be better in the intensively treated group (avg A1C=6.6) vs the "standard" group (A1C=7.7). The A1C was 8.3 in both groups at the start. These people all had diabetes for at least 10 years and weighed about 93kg, so they were a higher risk group for sure. Fewer heart attacks but more cardiovascular deaths in the intensive group, who took more diabetes drugs on the average. Not what they expected at all. Their LDL cholesterol was around 90 in both groups and didn't change, so I'm sure most were on statins. [/QUOTE]
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