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<blockquote data-quote="lindisfel" data-source="post: 988170" data-attributes="member: 57698"><p>Hi Steve,</p><p>In heart failure the body produce 5x the normal amount of aldosterone. That is why you are on Spironolactone.</p><p>My position with Aldosterone is far worse, I have Conn's syndrome and my body, due to an active adenoma on an adrenal gland, produces 20x the normal amount of aldosterone.</p><p>By cutting down on salt (sodium) and taking one of the two aldosterone antagonists one reduces the problems for the heart. </p><p>Aldosterone has caused fibrosis in my heart thats why I have a pacemaker and take warfarin for Afib.</p><p>Spiro and eplerenone, in time, can help reverse heart problems if it has not gone too far.</p><p></p><p>On the horizon there are new drugs that can help you and I. </p><p>Aldosterone synthase inhibitors will be crucial for those of us with too much Aldo. they are just round the corner and a young man like you could well get on a trial if your doctors thinks its OK.</p><p>If you google the above there are articles that will help you gain some insight in the hearts problems and A.S.I.s use to inhibit aldosterone at source.</p><p></p><p>regards</p><p></p><p>Derek</p></blockquote><p></p>
[QUOTE="lindisfel, post: 988170, member: 57698"] Hi Steve, In heart failure the body produce 5x the normal amount of aldosterone. That is why you are on Spironolactone. My position with Aldosterone is far worse, I have Conn's syndrome and my body, due to an active adenoma on an adrenal gland, produces 20x the normal amount of aldosterone. By cutting down on salt (sodium) and taking one of the two aldosterone antagonists one reduces the problems for the heart. Aldosterone has caused fibrosis in my heart thats why I have a pacemaker and take warfarin for Afib. Spiro and eplerenone, in time, can help reverse heart problems if it has not gone too far. On the horizon there are new drugs that can help you and I. Aldosterone synthase inhibitors will be crucial for those of us with too much Aldo. they are just round the corner and a young man like you could well get on a trial if your doctors thinks its OK. If you google the above there are articles that will help you gain some insight in the hearts problems and A.S.I.s use to inhibit aldosterone at source. regards Derek [/QUOTE]
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