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<blockquote data-quote="Winnie53" data-source="post: 837168" data-attributes="member: 160246"><p>Also came across this article today, "Should Patients Taking Metformin Also Take Vitamin B12?" - (if the link doesn't take you directly to the article, enter the article's title into Google....</p><p></p><p><a href="http://www.medscape.com/viewarticle/817601" target="_blank">http://www.medscape.com/viewarticle/817601</a></p><p></p><p><em>"Vitamin B12 deficiency is estimated to be present in up to 30% of patients with diabetes taking metformin. The risk for vitamin B12 deficiency increases with patient age and the dose and duration of metformin use. Concomitant conditions such as suboptimal dietary intake, which is common among vegetarians and alcohol abusers, and malabsorption due to atrophic gastritis, pernicious anemia, chronic pancreatitis, and celiac disease may further increase risk for vitamin B12 deficiency. The combination of metformin with proton pump inhibitors has been reported to have an additive effect on risk for vitamin B12 deficiency."</em> </p><p></p><p><em>"Measurement of serum vitamin B12 levels often produces both false-negative and false-positive results and is unreliable for diagnosis. Vitamin B12 deficiency can be treated with oral supplements or intramuscular injections depending on type and severity of deficiency."</em></p></blockquote><p></p>
[QUOTE="Winnie53, post: 837168, member: 160246"] Also came across this article today, "Should Patients Taking Metformin Also Take Vitamin B12?" - (if the link doesn't take you directly to the article, enter the article's title into Google.... [URL]http://www.medscape.com/viewarticle/817601[/URL] [I]"Vitamin B12 deficiency is estimated to be present in up to 30% of patients with diabetes taking metformin. The risk for vitamin B12 deficiency increases with patient age and the dose and duration of metformin use. Concomitant conditions such as suboptimal dietary intake, which is common among vegetarians and alcohol abusers, and malabsorption due to atrophic gastritis, pernicious anemia, chronic pancreatitis, and celiac disease may further increase risk for vitamin B12 deficiency. The combination of metformin with proton pump inhibitors has been reported to have an additive effect on risk for vitamin B12 deficiency."[/I] [I]"Measurement of serum vitamin B12 levels often produces both false-negative and false-positive results and is unreliable for diagnosis. Vitamin B12 deficiency can be treated with oral supplements or intramuscular injections depending on type and severity of deficiency."[/I] [/QUOTE]
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