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Message: <blockquote data-quote="Dark Horse" data-source="post: 2158066" data-attributes="member: 52527">This might be helpful:- 'HOMA apportions the basal state of insulin and glucose in terms of resistance and β-cell function. It can be seen from the model that for individuals with normal glucose levels, HOMA solutions might indicate 100% β-cell function and 100% insulin sensitivity, or, in the case of a thin, fit individual with high sensitivity, 50% β-cell function and 200% insulin sensitivity. Within the context of reporting both results, these are appropriate solutions—sensitivity is doubled, so the β-cells are functioning at 50% of normal. However, if the β-cell data are reported in isolation, one might conclude erroneously that the subject had failing β-cells, as opposed to appropriately low secretion, because the sensitivity of the body was high.' <a href="https://care.diabetesjournals.org/content/27/6/1487" target="_blank">https://care.diabetesjournals.org/content/27/6/1487</a></blockquote>

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