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How does protein affect blood glucose?
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<blockquote data-quote="phoenix" data-source="post: 824238" data-attributes="member: 12578"><p>I'll leave what I originally wrote but I thought I'd just check to see if there were any recent experiments with T1 . This one was published in February and they didn't find a significant rise from pure protein and that other studies had used mixed meals or high fat and protein meals (cat amongst pigeon time?)</p><p><a href="http://www.hindawi.com/journals/ije/2015/216918/" target="_blank"><u><span style="color: #0066cc">http://www.hindawi.com/journals/ije/2015/216918/</span></u></a></p><p>"In conclusion, the ingestion of a pure protein load does not seem to have a clinically significant impact on glucose levels in adult T1DM patients treated with insulin pumps. Thus, small protein-based snacks do not require prandial insulin blousing" </p><p></p><p> Ummm!</p><p></p><p><em>In a non diabetic eating protein causes a simultaneous release of insulin and glucagon .These to a certain extent counter balance each other in effect on blood glucose. This graph shows what happens ( bit small and not sure about the units) In non diabetics there is no immediate rise in glucose levels. </em></p><p><em>[ATTACH=full]12915[/ATTACH]</em></p><p><a href="http://www.medbio.info/horn/time%203-4/homeostasis_2.htm" target="_blank"><em>http://www.medbio.info/horn/time%203-4/homeostasis_2.htm</em></a></p><p><em> </em></p><p><em> There are experiments that also show no subsequent rise in glucose after protein ingestion in type 2s </em><a href="http://journal.diabetes.org/diabetesspectrum/00v13n3/pg132.htm" target="_blank"><em>http://journal.diabetes.org/diabetesspectrum/00v13n3/pg132.htm</em></a></p><p><em> In mixed meals added protein eg whey protein has been found to stimulate a higher insulin release in T2 diabetics resulting in a lower glucose level. </em><a href="http://ajcn.nutrition.org/content/82/1/69.full" target="_blank"><em>http://ajcn.nutrition.org/content/82/1/69.full</em></a></p><p><em></em></p><p><em> Do T1s get a glucagon/glycogen release ? Is your morning rise just due to the protein or are other 'morning' hormones involved? I agree about the effect of eggs?. 've always wondered if it has something to do with the proteins in eggs being more easily assimilable <em>Whey, according to the paper above elicits a high insulin release in non Ds and T2 subjects </em></em></p><p><em>but it could be something to do with the proportions of different amino acids. </em></p><p> <em></em></p><p><em> Gannon and Nuttall, also found that some amino acids raise insulin more than others. Some amino acids, not the same ones resulted in a higher glucagon release than others . There are also differences in resultant glucose concentrations </em></p><p><em>They end though by saying that it's all very complicated and not well understood .They don't know whether responses are different in T2 to normal subjects (and don't mention T1) </em><a href="http://onlinelibrary.wiley.com/doi/10.1002/iub.375/pdf" target="_blank"><u><em>http://onlinelibrary.wiley.com/doi/10.1002/iub.375/pdf</em></u></a></p></blockquote><p></p>
[QUOTE="phoenix, post: 824238, member: 12578"] I'll leave what I originally wrote but I thought I'd just check to see if there were any recent experiments with T1 . This one was published in February and they didn't find a significant rise from pure protein and that other studies had used mixed meals or high fat and protein meals (cat amongst pigeon time?) [URL='http://www.hindawi.com/journals/ije/2015/216918/'][U][COLOR=#0066cc]http://www.hindawi.com/journals/ije/2015/216918/[/COLOR][/U][/URL] "In conclusion, the ingestion of a pure protein load does not seem to have a clinically significant impact on glucose levels in adult T1DM patients treated with insulin pumps. Thus, small protein-based snacks do not require prandial insulin blousing" Ummm! [I]In a non diabetic eating protein causes a simultaneous release of insulin and glucagon .These to a certain extent counter balance each other in effect on blood glucose. This graph shows what happens ( bit small and not sure about the units) In non diabetics there is no immediate rise in glucose levels. [ATTACH=full]12915[/ATTACH][/I] [URL='http://www.medbio.info/horn/time%203-4/homeostasis_2.htm'][I]http://www.medbio.info/horn/time%203-4/homeostasis_2.htm[/I][/URL] [I] There are experiments that also show no subsequent rise in glucose after protein ingestion in type 2s [/I][URL='http://journal.diabetes.org/diabetesspectrum/00v13n3/pg132.htm'][I]http://journal.diabetes.org/diabetesspectrum/00v13n3/pg132.htm[/I][/URL] [I] In mixed meals added protein eg whey protein has been found to stimulate a higher insulin release in T2 diabetics resulting in a lower glucose level. [/I][URL='http://ajcn.nutrition.org/content/82/1/69.full'][I]http://ajcn.nutrition.org/content/82/1/69.full[/I][/URL] [I] Do T1s get a glucagon/glycogen release ? Is your morning rise just due to the protein or are other 'morning' hormones involved? I agree about the effect of eggs?. 've always wondered if it has something to do with the proteins in eggs being more easily assimilable [I]Whey, according to the paper above elicits a high insulin release in non Ds and T2 subjects [/I] but it could be something to do with the proportions of different amino acids. Gannon and Nuttall, also found that some amino acids raise insulin more than others. Some amino acids, not the same ones resulted in a higher glucagon release than others . There are also differences in resultant glucose concentrations They end though by saying that it's all very complicated and not well understood .They don't know whether responses are different in T2 to normal subjects (and don't mention T1) [/I][URL='http://onlinelibrary.wiley.com/doi/10.1002/iub.375/pdf'][U][I]http://onlinelibrary.wiley.com/doi/10.1002/iub.375/pdf[/I][/U][/URL] [/QUOTE]
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