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How fast does a glucose subcutaneous injection raise blood glucose?
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<blockquote data-quote="LooperCat" data-source="post: 2134034" data-attributes="member: 468055"><p>Glucose is very corrosive, so would cause damage if injected directly into tissue in a big dollop, as I understand it. When it’s injected into the bloodstream, it’s carried along in vessels with protective linings, essentially. As those vessels get smaller and smaller, the glucose can gently diffuse across into the interstitial fluid and then be transported into the cells to be burned for fuel. But a giant bolus of quite concentrated glucose dumped straight into tissue would be extremely harmful , and wouldn’t get it to where it needs to be. </p><p></p><p>Insulin and glucagon are hormones, so just small protein molecules which act on certain channels across the cell membrane. </p><p></p><p>I’m going to ask more about this when I’m in uni next week.</p></blockquote><p></p>
[QUOTE="LooperCat, post: 2134034, member: 468055"] Glucose is very corrosive, so would cause damage if injected directly into tissue in a big dollop, as I understand it. When it’s injected into the bloodstream, it’s carried along in vessels with protective linings, essentially. As those vessels get smaller and smaller, the glucose can gently diffuse across into the interstitial fluid and then be transported into the cells to be burned for fuel. But a giant bolus of quite concentrated glucose dumped straight into tissue would be extremely harmful , and wouldn’t get it to where it needs to be. Insulin and glucagon are hormones, so just small protein molecules which act on certain channels across the cell membrane. I’m going to ask more about this when I’m in uni next week. [/QUOTE]
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