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How long does Insulin take to drop levels?
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<blockquote data-quote="david252" data-source="post: 312216" data-attributes="member: 48369"><p>Oops, I missed the point of your question didn't I? <img src="data:image/gif;base64,R0lGODlhAQABAIAAAAAAAP///yH5BAEAAAAALAAAAAABAAEAAAIBRAA7" class="smilie smilie--sprite smilie--sprite10" alt=":oops:" title="Oops! :oops:" loading="lazy" data-shortname=":oops:" /> </p><p></p><p>The answer is not that straightforward in type 2 DM unfortunately. Levemir is a very long acting insulin and doesn't peak but gives a low basal or background level of insulin. There is also usually a high level of insulin resistance, so higher doses are needed and it also takes 3 days to see the full effect of any dose increase as the doses overlap - levemir lasts 24 to 36 hours and possibly longer in some people. Hence increments are done gradually, usually no faster than one dose change every 3 days and it takes time. </p><p></p><p>Unfortunately insulin also tends to make you gain weight, thereby increasing your insulin demand and hence you need to increase the dose further etc etc. I have seen type 2 that have NEVER managed to get their blood sugars down. Levemir is a relatively new insulin and is meant to not cause weight gain and this vicious spiraling upwards of demand (although this has not been clinically proven). So give it time - it may take several weeks potentially (anything less is a bonus) and keep an eye on your weight (which really is the most important thing). Any weight loss would be a bonus ( I appreciate it is very difficult (because of the reasons already mentioned) but whatever else, do your best not to GAIN any weight.</p></blockquote><p></p>
[QUOTE="david252, post: 312216, member: 48369"] Oops, I missed the point of your question didn't I? :oops: The answer is not that straightforward in type 2 DM unfortunately. Levemir is a very long acting insulin and doesn't peak but gives a low basal or background level of insulin. There is also usually a high level of insulin resistance, so higher doses are needed and it also takes 3 days to see the full effect of any dose increase as the doses overlap - levemir lasts 24 to 36 hours and possibly longer in some people. Hence increments are done gradually, usually no faster than one dose change every 3 days and it takes time. Unfortunately insulin also tends to make you gain weight, thereby increasing your insulin demand and hence you need to increase the dose further etc etc. I have seen type 2 that have NEVER managed to get their blood sugars down. Levemir is a relatively new insulin and is meant to not cause weight gain and this vicious spiraling upwards of demand (although this has not been clinically proven). So give it time - it may take several weeks potentially (anything less is a bonus) and keep an eye on your weight (which really is the most important thing). Any weight loss would be a bonus ( I appreciate it is very difficult (because of the reasons already mentioned) but whatever else, do your best not to GAIN any weight. [/QUOTE]
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