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Diabetes Discussion
Type 1.5/LADA Diabetes
How many different 'types' are there? Diagnoses Stories.
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<blockquote data-quote="Daibell" data-source="post: 731280" data-attributes="member: 21149"><p>I think there are so many different triggers, genes related issues and so on that it is impossible to correctly diagnose and classify many conditions. LADA is a conveniet grouping for those who weren't born with T1 but have developed T1 type symptoms between birth and death. The latest NICE DEC 2014 Diabetes Guidlelines recommend taking weight loss around diagnosis as a strong pointer to T1/LADA and not even bothering with the GAD/c-peptide tests. This makes some sense as it isn't only GAD anti-bodies that cause LADA. There are several other anti-bodies that aren't tested for and then there are pancreatic viruses, pancreatitis and so on. I think the only reliable thing is to assume that someone who is strongly overweight is very likely to be an insulin resistant T2 and if there is no evidence of excess weight then assume a T1 style diabetes needing insulin stimulating tablets and/or insulin. Yes, there is MODY, double-diabetes and so on as well just to add to the confusion. I presented as a thin person at diagnosis with very high blood sugar (measured by GP with urine stick!) but I knew I was hyper and I was labelled as a T2 and still am). Using the latest NICE guidelines I would come out as a LADA and fitting in the 15% of 'T2s' that are mis-diagnosed. It's far too convenient for the NHS, DUK and so on to use the two categories of T1 and T2. Note that DUK doesn't even acknowledge LADA.</p></blockquote><p></p>
[QUOTE="Daibell, post: 731280, member: 21149"] I think there are so many different triggers, genes related issues and so on that it is impossible to correctly diagnose and classify many conditions. LADA is a conveniet grouping for those who weren't born with T1 but have developed T1 type symptoms between birth and death. The latest NICE DEC 2014 Diabetes Guidlelines recommend taking weight loss around diagnosis as a strong pointer to T1/LADA and not even bothering with the GAD/c-peptide tests. This makes some sense as it isn't only GAD anti-bodies that cause LADA. There are several other anti-bodies that aren't tested for and then there are pancreatic viruses, pancreatitis and so on. I think the only reliable thing is to assume that someone who is strongly overweight is very likely to be an insulin resistant T2 and if there is no evidence of excess weight then assume a T1 style diabetes needing insulin stimulating tablets and/or insulin. Yes, there is MODY, double-diabetes and so on as well just to add to the confusion. I presented as a thin person at diagnosis with very high blood sugar (measured by GP with urine stick!) but I knew I was hyper and I was labelled as a T2 and still am). Using the latest NICE guidelines I would come out as a LADA and fitting in the 15% of 'T2s' that are mis-diagnosed. It's far too convenient for the NHS, DUK and so on to use the two categories of T1 and T2. Note that DUK doesn't even acknowledge LADA. [/QUOTE]
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