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how much does metformin actually help ?
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<blockquote data-quote="GrantGam" data-source="post: 1312566" data-attributes="member: 295621"><p>From the first link you provided:</p><p></p><p>"<em>The corresponding between-group differences in glycated hemoglobin (HbA1c) ranged from 0.6% to 2.0% at dosages of 500 to 2000 mg daily, respectively.</em>"</p><p></p><p>HbA1c used to be expressed as a percentage, and I think in this example is with reference to the DCCT units of measurement.</p><p></p><p>So a 2% reduction in HbA1c is (for example) 7% to 5% or 53mmol/mol to 31mmol/mol.</p><p></p><p>From the above example, a 2% decrease in HbA1c (measured in old DCCT standards) equates to a reduction of 22mmol/mol (measured in IFCC new standards).</p></blockquote><p></p>
[QUOTE="GrantGam, post: 1312566, member: 295621"] From the first link you provided: "[I]The corresponding between-group differences in glycated hemoglobin (HbA1c) ranged from 0.6% to 2.0% at dosages of 500 to 2000 mg daily, respectively.[/I]" HbA1c used to be expressed as a percentage, and I think in this example is with reference to the DCCT units of measurement. So a 2% reduction in HbA1c is (for example) 7% to 5% or 53mmol/mol to 31mmol/mol. From the above example, a 2% decrease in HbA1c (measured in old DCCT standards) equates to a reduction of 22mmol/mol (measured in IFCC new standards). [/QUOTE]
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