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How reliable are HbA1c tests?
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<blockquote data-quote="Lupf" data-source="post: 2224797" data-attributes="member: 518059"><p>Hi ziggy_w</p><p></p><p>thanks a lot. This is very useful. </p><p>Do I understand that CGMs are the metres, e.g. Dexcom G6, which measure just beneath your skin? </p><p>For illustration Hb1Ac measurement of 53 mmol/l corresponds to a CGM of 160 mg/dl on average.</p><p>The plot contains 95% intervals, but even if I eyeball a 67% interval (1 standard deviation)</p><p>you can get a variation of Hb1Ac values about 6 values up to 59 and down to 47 which also will </p><p>give CGM of 160. This is quite scary for two reasons.</p><p>1) When people fret about being below the diabetes threshold of 42, they could be off by a huge margin.</p><p>2) I would be surprised if all GPs know that there can be such large discrepancies between Hb1Ac and CGM. </p><p></p><p>I also read that for individuals the Hb1Ac variation is much more stable.</p><p>Thus I have to accept that for me the rise from 42 to 55 is real. Maybe Christmas where I did not resist sweets (which I usually do) and also not fast had a bigger impact on my Hb1Ac.</p></blockquote><p></p>
[QUOTE="Lupf, post: 2224797, member: 518059"] Hi ziggy_w thanks a lot. This is very useful. Do I understand that CGMs are the metres, e.g. Dexcom G6, which measure just beneath your skin? For illustration Hb1Ac measurement of 53 mmol/l corresponds to a CGM of 160 mg/dl on average. The plot contains 95% intervals, but even if I eyeball a 67% interval (1 standard deviation) you can get a variation of Hb1Ac values about 6 values up to 59 and down to 47 which also will give CGM of 160. This is quite scary for two reasons. 1) When people fret about being below the diabetes threshold of 42, they could be off by a huge margin. 2) I would be surprised if all GPs know that there can be such large discrepancies between Hb1Ac and CGM. I also read that for individuals the Hb1Ac variation is much more stable. Thus I have to accept that for me the rise from 42 to 55 is real. Maybe Christmas where I did not resist sweets (which I usually do) and also not fast had a bigger impact on my Hb1Ac. [/QUOTE]
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