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How to avoid pain while injecting the insulin injection ?
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<blockquote data-quote="PseudoBob77" data-source="post: 1185919" data-attributes="member: 198770"><p>Insulin potency</p><p>Potency is the effectiveness of insulin to lower blood glucose. Potency </p><p>decreases with exposure to light, temperature and vibration, so </p><p>correct storage of your insulin is important. In-use insulin not stored </p><p>in the fridge has been exposed to all these factors so its potency may </p><p>be reduced and this is why it should be discarded after 28 days [less </p><p>with certain insulins]. </p><p>The following facts are known [ref1]</p><p>• The potency of insulin decreases very gradually over time and the </p><p>degree of reduction depends on the storage conditions.</p><p>• Insulin should be stored in the dark as exposure to sunlight </p><p>decreases its biological activity. The optimum storage is in the dark </p><p>at temperatures between 2 and 8°C. Freezing must be avoided as </p><p>it can destroy the insulin.</p><p>• If there is a loss of potency as a result of storage at high temperatures </p><p>for long periods, then the breakdown products of insulin are not </p><p>harmful in any way - unlike expired antibiotics, for example. So the </p><p>insulin is safe to use but it may not be fully effective. </p><p>The table below shows the extremely long periods of time before the </p><p>potency is reduced by even small amounts – no similar figures are </p><p>available for analogue insulins.</p><p>Time of storage of insulin preparations at various temperatures </p><p>until biological potency is reduced by 2% and 5% respectively</p><p>Insulin </p><p>preparation</p><p>4°C 15°C 25°C 40°C</p><p>Actrapid 36/92 years 5/13 years 12/31 </p><p>months</p><p>5/14 weeks</p><p>Semilente 45/115 </p><p>years</p><p>4/11 years 7/18 </p><p>months</p><p>2/5 weeks</p><p>Lente 36/91 years 3/9 years 5/14 </p><p>months</p><p>1/ 4 weeks</p><p>Rapitard 22/55 years 3/8 years 7/17 </p><p>months</p><p>3/7 weeks</p><p>Ultralente 19/48 years 2/5 years 4/10 </p><p>months</p><p>1/3 weeks</p><p> </p><p>Information source: ‘Galenics of Insulin’ by J Brange M.Sc et al: [Novo </p><p></p><p></p><p>Sent from my SM-G900F using <a href="http://r.tapatalk.com/byo?rid=67" target="_blank">Diabetes.co.uk Forum mobile app</a></p></blockquote><p></p>
[QUOTE="PseudoBob77, post: 1185919, member: 198770"] Insulin potency Potency is the effectiveness of insulin to lower blood glucose. Potency decreases with exposure to light, temperature and vibration, so correct storage of your insulin is important. In-use insulin not stored in the fridge has been exposed to all these factors so its potency may be reduced and this is why it should be discarded after 28 days [less with certain insulins]. The following facts are known [ref1] • The potency of insulin decreases very gradually over time and the degree of reduction depends on the storage conditions. • Insulin should be stored in the dark as exposure to sunlight decreases its biological activity. The optimum storage is in the dark at temperatures between 2 and 8°C. Freezing must be avoided as it can destroy the insulin. • If there is a loss of potency as a result of storage at high temperatures for long periods, then the breakdown products of insulin are not harmful in any way - unlike expired antibiotics, for example. So the insulin is safe to use but it may not be fully effective. The table below shows the extremely long periods of time before the potency is reduced by even small amounts – no similar figures are available for analogue insulins. Time of storage of insulin preparations at various temperatures until biological potency is reduced by 2% and 5% respectively Insulin preparation 4°C 15°C 25°C 40°C Actrapid 36/92 years 5/13 years 12/31 months 5/14 weeks Semilente 45/115 years 4/11 years 7/18 months 2/5 weeks Lente 36/91 years 3/9 years 5/14 months 1/ 4 weeks Rapitard 22/55 years 3/8 years 7/17 months 3/7 weeks Ultralente 19/48 years 2/5 years 4/10 months 1/3 weeks Information source: ‘Galenics of Insulin’ by J Brange M.Sc et al: [Novo Sent from my SM-G900F using [URL=http://r.tapatalk.com/byo?rid=67]Diabetes.co.uk Forum mobile app[/URL] [/QUOTE]
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