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How to split Levemir dose
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<blockquote data-quote="mike@work" data-source="post: 2152357" data-attributes="member: 487115"><p>[USER=505889]@Lynne211[/USER] </p><p></p><p>Taken from</p><p></p><p><a href="http://www.diabetes-book.com/laws-small-numbers/" target="_blank">http://www.diabetes-book.com/laws-small-numbers/</a></p><p></p><p>"Dr. Galloway then measured blood sugars every few minutes and adjusted the glucose drip to keep the patient’s blood sugars clamped at 90 mg/dl. How long would you guess the glucose infusion had to be continued to prevent dangerously low blood sugars, or hypoglycemia?</p><p></p><p>It took a week, even though the package insert says that regular insulin lasts only 4–12 hours. So the conclusion is that even the timing of injected insulin is very much dependent upon how much was injected. In practice, larger insulin injections start working sooner, last longer, and have less predictable timing."</p><p></p><p>I have tested myself with both Levemir and Hypurin Porcine Isophane, and bigger doses gives a bit longer action-time. On the other hand: One also have to take into account all other matters that can influence action time for Insulin, such as where it is injected and so on. And then there is the obvious problem, that bigger doses, can start to give very powerful hypos.</p><p>And please, no need to shout...</p><p></p><p>Edited to insert tag and to correct some typos.</p></blockquote><p></p>
[QUOTE="mike@work, post: 2152357, member: 487115"] [USER=505889]@Lynne211[/USER] Taken from [URL]http://www.diabetes-book.com/laws-small-numbers/[/URL] "Dr. Galloway then measured blood sugars every few minutes and adjusted the glucose drip to keep the patient’s blood sugars clamped at 90 mg/dl. How long would you guess the glucose infusion had to be continued to prevent dangerously low blood sugars, or hypoglycemia? It took a week, even though the package insert says that regular insulin lasts only 4–12 hours. So the conclusion is that even the timing of injected insulin is very much dependent upon how much was injected. In practice, larger insulin injections start working sooner, last longer, and have less predictable timing." I have tested myself with both Levemir and Hypurin Porcine Isophane, and bigger doses gives a bit longer action-time. On the other hand: One also have to take into account all other matters that can influence action time for Insulin, such as where it is injected and so on. And then there is the obvious problem, that bigger doses, can start to give very powerful hypos. And please, no need to shout... Edited to insert tag and to correct some typos. [/QUOTE]
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