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Hypertension as a risk for type 2?
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<blockquote data-quote="SimonCrox" data-source="post: 1955150" data-attributes="member: 388174"><p>Totally agree with the above; syndrome X is the clustering of hypertension, Type 2 diabetes, dyslipidaemia and several other things which are probably linked by insulin resistance.</p><p>Blood pressure reduction itself probably does not alter risk of future diabetes, but some BP treatments eg thiazides and beta blockers increase diabetes risk, and others eg calcium channel blockers and alpha blockers are probably neutral and some drugs eg ACE inhibitors and sartans might be a bit protective against future diabetes. </p><p>How the insulin resistance and associated hyperinsulinaemia cause hypertension is not exactly known - as above, it increases salt retention via the kidneys, and increases the resistance of blood vessles, but there are probably other factors.</p><p>So tricks to reduce insulin resistance eg weight loss and exercise help both blood pressure and diabetes risk.</p><p>best wishes</p></blockquote><p></p>
[QUOTE="SimonCrox, post: 1955150, member: 388174"] Totally agree with the above; syndrome X is the clustering of hypertension, Type 2 diabetes, dyslipidaemia and several other things which are probably linked by insulin resistance. Blood pressure reduction itself probably does not alter risk of future diabetes, but some BP treatments eg thiazides and beta blockers increase diabetes risk, and others eg calcium channel blockers and alpha blockers are probably neutral and some drugs eg ACE inhibitors and sartans might be a bit protective against future diabetes. How the insulin resistance and associated hyperinsulinaemia cause hypertension is not exactly known - as above, it increases salt retention via the kidneys, and increases the resistance of blood vessles, but there are probably other factors. So tricks to reduce insulin resistance eg weight loss and exercise help both blood pressure and diabetes risk. best wishes [/QUOTE]
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