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I fixed hashimotos, maculopathy, + dawn phenomenom in a few months
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<blockquote data-quote="RobynV" data-source="post: 2648483" data-attributes="member: 581272"><p>Yes you are absolutely right. Hence I noted there were caveats. These meds are ‘easier’ to tolerate these days as have been refined (info from heart/lung transplant patients who lived a long time). However if stem cell therapy can eventually be applied - and/or DNA technology called ‘Crisper’ (literally cuts and rejoins and if nec - inserts new DNA) - then immunosuppressants will not be needed. Stem cell therapy (autologous - ie own cells) already on market - more research needed for complex cell types. Crisper is the basis of all the so-called GM (gene modified) foods - and ‘successful’ for years now. Humans - they already use Crisper to delete poor DNA in a couple of terrible diseases in young children. Very specific DNA mods. Nearly 100% success rate. And then they live a normal life. Trials ca 5 yr point. Crisper has been around a while (>10yrs). It’s a matter of funding for research - and the transplant academics are technically in competition with the other crowd. Which part of ‘cell production’ line will need to be edited / reproduced in a baby/child? Don’t know. But the principles behind this research theoretically will treat a myriad of ‘born with’ conditions. So funding competition also in that respect. Complexity of islets (or their precursors; or post - late onset T1) is another issue. Science / gov funders will fund the ‘sexy’ research first. These first Crisper cases are treating very rare diseases. Possibly there’s an economic argument for DB1. I was trying to signal hope. I also have impression T1s on this site seem to get things under control (better?) than other types. Which would lessen ec argument. Possibly. Could be wrong.</p></blockquote><p></p>
[QUOTE="RobynV, post: 2648483, member: 581272"] Yes you are absolutely right. Hence I noted there were caveats. These meds are ‘easier’ to tolerate these days as have been refined (info from heart/lung transplant patients who lived a long time). However if stem cell therapy can eventually be applied - and/or DNA technology called ‘Crisper’ (literally cuts and rejoins and if nec - inserts new DNA) - then immunosuppressants will not be needed. Stem cell therapy (autologous - ie own cells) already on market - more research needed for complex cell types. Crisper is the basis of all the so-called GM (gene modified) foods - and ‘successful’ for years now. Humans - they already use Crisper to delete poor DNA in a couple of terrible diseases in young children. Very specific DNA mods. Nearly 100% success rate. And then they live a normal life. Trials ca 5 yr point. Crisper has been around a while (>10yrs). It’s a matter of funding for research - and the transplant academics are technically in competition with the other crowd. Which part of ‘cell production’ line will need to be edited / reproduced in a baby/child? Don’t know. But the principles behind this research theoretically will treat a myriad of ‘born with’ conditions. So funding competition also in that respect. Complexity of islets (or their precursors; or post - late onset T1) is another issue. Science / gov funders will fund the ‘sexy’ research first. These first Crisper cases are treating very rare diseases. Possibly there’s an economic argument for DB1. I was trying to signal hope. I also have impression T1s on this site seem to get things under control (better?) than other types. Which would lessen ec argument. Possibly. Could be wrong. [/QUOTE]
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